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Table 1 Key population and epidemiology inputs, MSM population

From: Investigating zero transmission of HIV in the MSM population: a UK modelling case study

Input

Value

Source

Initial population, N

621,210

BASHH 2020, [17] ONS 2018 [18]

MSMLWH population, % (n)

8.097 (50,299)

Public Health England 2020 [16]

 Undiagnosed MSMLWH, % (n)

5.77 (2,902)

Public Health England 2020 [16]

 Diagnosed MSMLWH, % (n)

94.23 (47,397)

Public Health England 2020 [16]

PrEP users, % of HIV-negative population (n)

4.326 (24,698)

Public Health England 2020, [16] Expert Opinion

Efficacy of PrEP, %

86.00

Cambiano et al., 2018 [19]

Treated population, % of diagnosed population (n)

98.44 (46,658)

Public Health England, 2020 [16]

MSMLWH who are virologically suppressed, % of treated population (n)

97.00 (45,258)

Public Health England, 2020 [16]

Initial health state distribution, undiagnosed population, % (n)

 CD4 > 500

45.80 (1,329)

Public Health England, 2020 [16]

 500 ≥ CD4 ≥ 350

19.06 (553)

Public Health England, 2020 [16]

 350 > CD4 > 200

1.04 (30)

Public Health England, 2020 [16]

 CD4 ≤ 200

34.10 (990)

Public Health England, 2020 [16]

Initial health state distribution, not on treatment population, % (n)

 CD4 > 500

45.80 (339)

Public Health England, 2020 [16]

 500 ≥ CD4 ≥ 350

19.06 (141)

Public Health England, 2020 [16]

 350 > CD4 ≥ 200

1.04 (8)

Public Health England, 2020 [16]

 CD4 < 200

34.10 (252)

Public Health England, 2020 [16]

  1. Footnotes: CD4 counts are in cells/µL. BASHH: British Association for Sexual Health and HIV; MSM: men who have sex with men; MSMLWH: men who have sex with men living with HIV; ONS: Office for National Statistics; PrEP: pre-exposure prophylaxis