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Table 3 Uni-variablea and multivariableb logistic regression for predictors of treatment failure of TB in Khambhat block (n = 2748)

From: Silicosis as a predictor of tuberculosis mortality and treatment failure and need for incorporation in differentiated TB care models in India

Variables

Crude OR (95% CI)

p-value

Adjusted OR (95% CI)

p-value

Concomitant silicosis

5 (3–10)

 < 0.001

3 (1.4–6.5)

0.005

Age (years)

0.9 (0.9–1)

0.448

-

-

Male gender

2.3 (1.1–4.5)

0.021

2 (0.9–3.8)

0.076

Weight (n = 829)

1.01 (0.9–1.1)

0.692

-

-

HIV positive

1.1 (0.2–8.4)

0.900

-

-

Diabetes

1.5 (0.9–2.6)

0.130

1.4 (0.8–2.6)

0.218

Previously treated for TB

2.5 (1.4–4.3)

0.001

3 (2–6)

 < 0.001

Multi-drug resistant TB

15 (8–31)

 < 0.001

18 (8–41)

 < 0.001

  1. HIV Human immunodeficiency virus, TB Tuberculosis, OR Odds ratio, CI Confidence intervals
  2. asputum positive TB and extra-pulmonary TB were removed from the analysis due to lack of data in the comparison group
  3. bModel statistics: Omnibus chi-square = 68 (p-value < 0.001); Hosmer–Lemeshow p-value = 0.279; Nagelkerke r2 = 0.139; classification accuracy = 98%