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Table 3 The subgroup analysis of the associations between lean body mass, visceral fat mass and lean body mass to visceral fat ratio with bone mineral density in the National Health and Nutrition Examination Survey 2011–2018

From: Association between lean body mass to visceral fat mass ratio and bone mineral density in United States population: a cross-sectional study

Independent variables

Per-SD increase

β (95% CI)

Quartile β (95% CI)

Q1

Q2

Q3

Q4

Total lean mass

     

Stratified by gender

     

 Male

0.086 (0.081, 0.092) a

Reference

0.057 (0.040, 0.075) a

0.097 (0.080, 0.115) a

0.153 (0.134, 0.171) a

 Female

0.082 (0.076, 0.089) a

Reference

0.054 (0.048, 0.061) a

0.091 (0.080, 0.101)a

0.108 (0.092, 0.124) a

Stratified by age

     

 <50

0.079 (0.075, 0.084) a

Reference

0.050 (0.044, 0.056) a

0.087 (0.079, 0.095) a

0.139 (0.129, 0.150) a

 ≥50

0.074 (0.065, 0.084) a

Reference

0.052 (0.039, 0.066) a

0.080 (0.063, 0.098) a

0.133 (0.111, 0.156) a

BMI

     

 <25

0.091 (0.083, 0.098) a

Reference

0.056 (0.046, 0.066) a

0.099 (0.087, 0.112) a

0.153 (0.133, 0.173) a

 25–30

0.082 (0.074, 0.089) a

Reference

0.052 (0.042, 0.062) a

0.094 (0.079, 0.109) a

0.145 (0.129, 0.162) a

 ≥30

0.044 (0.039, 0.049) a

Reference

0.040 (0.026, 0.055) a

0.064 (0.048, 0.079) a

0.107 (0.090, 0.124) a

Stratified by hypertension

     

 Yes

0.077 (0.068, 0.085) a

Reference

0.053 (0.038, 0.067) a

0.083 (0.067, 0.100) a

0.131 (0.110, 0.152) a

 No

0.082 (0.077, 0.086) a

Reference

0.053 (0.047, 0.060) a

0.092 (0.084, 0.101) a

0.146 (0.135, 0.156) a

Stratified by diabetes

     

 Yes

0.068 (0.056, 0.081) a

Reference

0.065 (0.043, 0.087) a

0.095 (0.070, 0.120) a

0.135 (0.104, 0.167) a

 No

0.083 (0.078, 0.087) a

Reference

0.051 (0.045, 0.058) a

0.089 (0.081, 0.097) a

0.143 (0.133, 0.154) a

Visceral fat mass

     

Stratified by gender

     

 Male

-0.036 (-0.040, -0.031) a

Reference

-0.025 (-0.033, -0.017) a

-0.042 (-0.052, -0.032) a

-0.082 (-0.094, -0.070) a

 Female

-0.022 (-0.026, -0.017) a

Reference

-0.014 (-0.022, -0.007) a

-0.025 (-0.033, -0.016) a

-0.048 (-0.059, -0.037) a

Stratified by age

     

 <50

-0.029 (-0.032, -0.025) a

Reference

-0.019 (-0.025, -0.013) a

-0.030 (-0.037, -0.023) a

-0.064 (-0.072, -0.055) c

 ≥50

-0.022 (-0.028, -0.016) a

Reference

-0.021 (-0.039, -0.003) a

-0.031 (-0.049, -0.013) a

-0.054 (-0.073, -0.035) a

BMI

     

 <25

-0.030 (-0.038, -0.022) a

Reference

-0.015 (-0.022, -0.007) a

-0.034 (-0.046, -0.023) a

-0.075 (-0.098, -0.052) a

 25–30

-0.036 (-0.043, -0.030) a

Reference

-0.031 (-0.042, -0.019) a

-0.050 (-0.062, -0.038) a

-0.082 (-0.097, -0.068) a

 ≥30

-0.017 (-0.020, -0.013) a

Reference

-0.030 (-0.048, -0.012) c

-0.035 (-0.052, -0.017) a

-0.059 (-0.077, -0.041) a

Stratified by hypertension

     

 Yes

-0.019 (-0.024, -0.014) a

Reference

-0.014 (-0.031, 0.003)

-0.022 (-0.039, -0.005) c

-0.045 (-0.064, -0.026) a

 No

-0.034 (-0.037, -0.030) a

Reference

-0.022 (-0.028, -0.016) a

-0.037 (-0.044, -0.030) a

-0.072 (-0.081, -0.063) a

Stratified by diabetes

     

 Yes

-0.005 (-0.012, 0.002)

Reference

0.021 (-0.017, 0.058)

0.014 (-0.022, 0.049)

0.011 (-0.026, 0.047)

 No

-0.032 (-0.035, -0.028) a

Reference

-0.023 (-0.029, -0.018) a

-0.036 (-0.043, -0.029) a

-0.072 (-0.081, -0.064) a

LogLM/VFM

     

Stratified by gender

     

 Male

0.053 (0.049, 0.058) a

Reference

0.046 (0.038, 0.054) a

0.077 (0.068, 0.085) a

0.112 (0.102, 0.123) a

 Female

0.024 (0.021, 0.027) a

Reference

0.030 (0.023, 0.037) a

0.039 (0.032, 0.047) a

0.062 (0.053, 0.071) a

Stratified by age

     

 <50

0.030 (0.028, 0.033) a

Reference

0.029 (0.024, 0.035) a

0.050 (0.044, 0.056) a

0.077 (0.069, 0.084) a

 ≥50

0.035 (0.029, 0.041) a

Reference

0.042 (0.031, 0.052)

0.051 (0.038, 0.064) a

0.073 (0.055, 0.092) a

BMI

     

 <25

0.026 (0.022, 0.030) a

Reference

0.029 (0.014, 0.044) a

0.048 (0.033, 0.062) a

0.076 (0.060, 0.091) a

 25–30

0.045 (0.040, 0.050) a

Reference

0.047 (0.038, 0.056) a

0.067 (0.058, 0.077) a

0.101 (0.088, 0.114) a

 ≥30

0.041 (0.036, 0.046) a

Reference

0.032 (0.024, 0.040) a

0.055 (0.046, 0.065) a

0.089 (0.074, 0.103) a

Stratified by hypertension

     

 Yes

0.036 (0.030, 0.042) a

Reference

0.045 (0.035, 0.055) a

0.058 (0.046, 0.071) a

0.077 (0.060, 0.094) a

 No

0.034 (0.031, 0.037) a

Reference

0.032 (0.026, 0.038) a

0.055 (0.048, 0.061) a

0.084 (0.077, 0.092) a

Stratified by diabetes

     

 Yes

0.022 (0.012, 0.032) a

Reference

0.018 (0.003, 0.034) c

0.030 (0.008, 0.051) b

0.019 (-0.014, 0.053)

 No

0.036 (0.033, 0.039) a

Reference

0.040 (0.034, 0.045) a

0.060 (0.054, 0.066) a

0.090 (0.083, 0.098) a

  1. Abbreviations: β partial regression coefficient, CI confidence interval, BMD bone mineral density, LM/VFM lean body mass/visceral fat mass
  2. All variables including gender, age and race were adjusted. Model 2: gender, age, marital status, race, education, PIR, BMI, activity, MET scores, smoking, alcohol, hypertension, diabetes, thyroid disease, serum vitamin D, total cholesterol, alanine aminotransferase, total calcium, serum uric acid, vitamin D intake, vitamin D supplements, calcium intake, and calcium supplements were adjusted for, except for the stratification variable which was not adjusted for
  3. a P < 0.001, b P < 0.01, c P < 0.05