Table 3 Unadjusted and adjusted poisoning incidence rate ratios
Poisoning incidence rate ratios (95% confidence intervals) | ||||||||
|---|---|---|---|---|---|---|---|---|
All medicinal poisonings combined | Paracetamol (T39.1) | Other OTC analgesia/anti-common cold drugs (T39.0, T39.3, T48.5‡) | Dependence/withdrawal risk drugs (T40.2, T40.3, T40.4, T42.4, T42.6, T43.0, T43.1, T43.2‡) | |||||
Unadjusted IRRs | Adjusted IRRs* | Unadjusted IRRs | Adjusted IRRs* | Unadjusted IRRs | Adjusted IRRs* | Unadjusted IRRs | Adjusted IRRs* | |
Sex | ||||||||
Male | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Female | 0.93 (0.86–1.00) | 0.93 (0.87–0.99) | 0.92 (0.82–1.03) | 0.98 (0.83–1.16) | 1.18 (0.95–1.45) | 1.16 (0.96–1.40) | 0.97 (0.78–1.20) | 0.96 (0.79–1.15) |
Age group (years) | ||||||||
0–4 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
5–11 | 0.10 (0.09–0.11) | 0.10 (0.09–0.11) | 0.08 (0.07–0.10) | 0.08 (0.07–0.10) | 0.05 (0.03–0.07) | 0.05 (0.03–0.07) | 0.10 (0.07–0.13) | 0.10 (0.07–0.13) |
Calendar period | ||||||||
1998/99-2002/03 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
2003/04-2007/08 | 0.87 (0.79–0.96) | 0.89 (0.82–0.98) | 0.96 (0.81–1.14) | 0.98 (0.83–1.16) | 0.98 (0.73–1.32) | 1.00 (0.77–1.29) | 0.65 (0.48–0.87) | 0.70 (0.54–0.90) |
2008/09-2012/13 | 0.81 (0.73–0.90) | 0.82 (0.75–0.90) | 1.12 (0.96–1.32) | 1.10 (0.93–1.29) | 0.81 (0.60–1.09) | 0.82 (0.63–1.07) | 0.56 (0.42–0.75) | 0.61 (0.47–0.79) |
2013/14-2017/18 | 0.90 (0.80-1.00) | 0.97 (0.88–1.07) | 1.38 (1.16–1.63) | 1.43 (1.20–1.70) | 0.72 (0.51–1.01) | 0.82 (0.60–1.12) | 0.55 (0.39–0.77) | 0.67 (0.50–0.90) |
Test for trend | p = 0.01 | p = 0.11 | p < 0.0001 | p < 0.0001 | p = 0.02 | p = 0.09 | p = 0.0001 | p = 0.001 |
Socio-economic deprivation quintile† | ||||||||
1 (least deprived) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
2 | 1.23 (1.08–1.41) | 1.19 (1.05–1.34) | 1.04 (0.86–1.27) | 1.01 (0.83–1.23) | 1.18 (0.82–1.70) | 1.15 (0.82–1.61) | 1.34 (0.89–2.02) | 1.26 (0.86–1.85) |
3 | 1.20 (1.06–1.37) | 1.12 (0.99–1.26) | 1.04 (0.86–1.27) | 0.95 (0.78–1.16) | 0.83 (0.56–1.21) | 0.79 (0.55–1.13) | 1.36 (0.91–2.04) | 1.22 (0.83–1.79) |
4 | 1.38 (1.22–1.57) | 1.31 (1.16–1.47) | 1.06 (0.88–1.28) | 1.07 (0.88–1.30) | 1.16 (0.81–1.65) | 1.10 (0.79–1.53) | 2.36 (1.62–3.43) | 2.03 (1.42–2.88) |
5 (most deprived) | 1.76 (1.56–1.99) | 1.32 (1.18–1.47) | 1.31 (1.09–1.56) | 1.06 (0.88–1.28) | 1.67 (1.20–2.33) | 1.27 (0.92–1.74) | 2.70 (1.88–3.89) | 1.88 (1.32–2.66) |
Test for trend | p < 0.0001 | p < 0.0001 | p = 0.002 | p = 0.38 | p = 0.001 | p = 0.15 | p < 0.0001 | p < 0.0001 |