Table 2 Heterogeneity and horizontal pleiotropy tests for causal effects of childhood obesity on Alzheimer’s disease
From: Childhood obesity and risk of Alzheimer’s disease: a Mendelian randomization study
Method | Heterogeneity | Horizontal pleiotropy | ||||
|---|---|---|---|---|---|---|
Q | df | p value | Egger intercept | Egger SE | p value | |
Alzheimer’s disease | ||||||
MR Egger | 12.29791 | 12 | 0.422 | 0.000 | 0.022 | 0.992 |
IVW | 12.29801 | 13 | 0.503 | |||
Alzheimer’s disease-repeated | ||||||
MR Egger | 21.23890 | 12 | 0.077 | 0.019 | 0.016 | 0.282 |
IVW | 23.48531 | 13 | 0.087 | |||