Table 2 Univariate analysis of factors associated with mother-to-child transmission of HIV-1 at 6 weeks and at 6 months of life
Variables | Infant HIV-1 status at 6 weeks | Infant HIV-1 status at 6 months | ||||||
|---|---|---|---|---|---|---|---|---|
n | HIV-(%) | HIV + (%) | P-value | N | HIV-(%) | HIV + (%) | P-value | |
Mother’s age, years | ||||||||
<=24 | 202 | 95.5 | 4.5 | 0.317 | 202 | 94.6 | 5.4 | 0.117 |
>24 | 477 | 97.1 | 2.9 | 473 | 97.0 | 3.0 | ||
Marital status | ||||||||
married | 562 | 97.7 | 2.3 | 0.001 | 559 | 97.5 | 2.5 | 0.000 |
unmarried | 117 | 91.5 | 8.5 | 116 | 90.5 | 9.5 | ||
Education | ||||||||
none/primary | 509 | 96.5 | 3.5 | 0.710 | 508 | 96.3 | 3.7 | 0.930 |
secondary/university | 170 | 97.1 | 2.9 | 167 | 96.4 | 3.6 | ||
Wealth | ||||||||
poorest | 175 | 94.3 | 5.7 | 0.328 | 174 | 94.3 | 5.7 | 0.459 |
second | 99 | 98.0 | 2.0 | 99 | 98.0 | 2.0 | ||
middle | 143 | 97.2 | 2.8 | 143 | 97.2 | 2.8 | ||
fourth | 145 | 96.6 | 3.4 | 144 | 95.8 | 4.2 | ||
richest | 117 | 98.3 | 1.7 | 115 | 97.4 | 2.6 | ||
Parity | ||||||||
primipara | 146 | 93.2 | 6.8 | 0.009 | 144 | 91.7 | 8.3 | 0.001 |
multiparous | 533 | 97.6 | 2.4 | 531 | 97.6 | 2.4 | ||
Disclosed HIV status to partner | ||||||||
Yes | 551 | 98.2 | 1.8 | 0.000 | 550 | 97.8 | 2.2 | 0.000 |
No | 128 | 89.8 | 10.2 | 125 | 89.6 | 10.4 | ||
Place of delivery | ||||||||
home | 20 | 90.0 | 10.0 | 0.097 | 20 | 90.0 | 10.0 | 0.130 |
facility | 659 | 96.8 | 3.2 | 655 | 96.5 | 3.5 | ||
Sex of the infant | ||||||||
male | 335 | 96.7 | 3.3 | 0.883 | 332 | 96.4 | 3.6 | 0.904 |
female | 344 | 96.5 | 3.5 | 343 | 96.2 | 3.8 | ||
Type of feeding during first 6 months of life | ||||||||
exclusive breastfeeding | 585 | 96.8 | 3.2 | 0.070 | 581 | 96.6 | 3.4 | 0.002 |
artificial feeding | 80 | 97.5 | 2.5 | 80 | 97.5 | 2.5 | ||
mixt feeding | 14 | 85.7 | 14.3 | 14 | 78.6 | 21.4 | ||
Mode of delivery | ||||||||
vaginal/instrument assisted | 558 | 96.4 | 3.6 | 0.542 | 554 | 96.0 | 4.0 | 0.431 |
cesarean section | 121 | 97.5 | 2.5 | 121 | 97.5 | 2.5 | ||
Hemoglobin during pregnancy | ||||||||
<11 g/dl | 180 | 93.3 | 6.7 | 0.005 | 179 | 93.9 | 6.1 | 0.044 |
> = 11 g/dl | 499 | 97.8 | 2.2 | 496 | 97.2 | 2.8 | ||
Type of ARV treatment | ||||||||
prophylactic | 352 | 97.4 | 2.6 | 0.215 | 350 | 96.9 | 3.1 | 0.423 |
curative | 327 | 95.7 | 4.3 | 325 | 95.7 | 4.3 | ||
Duration of ARV treatment prior to delivery | ||||||||
less than 6 weeks | 153 | 93.5 | 6.5 | 0.014 | 152 | 94.1 | 5.9 | 0.100 |
6 weeks or more | 526 | 97.5 | 2.5 | 523 | 96.9 | 3.1 | ||
CD4 count | ||||||||
<350 cells/mm3 | 263 | 94.3 | 5.7 | 0.009 | 261 | 94.3 | 5.7 | 0.028 |
> = 350 cells/mm3 | 416 | 98.1 | 1.9 | 414 | 97.6 | 2.4 | ||
Viral load | ||||||||
<1000 copies/ml | 517 | 98.6 | 1.4 | 0.000 | 514 | 98.1 | 1.9 | 0.000 |
> = 1000 copies/ml | 162 | 90.1 | 9.9 | 161 | 90.7 | 9.3 | ||