Table 4 Covariates, effects modifiers and descriptive variables of the PSYCHOTSH study

Association of elevation of TSH and impaired

Elevation of TSH

Neurodevelopment and/or psychometric testing

Neurodevelopment

Foetus in utero exposure to:

Foetus in utero exposure to:

Child related factor:

Zip code of the house of the child

Child bilinguism

Iodine excess

Iodine containing drugs

Chronic disease of the child

Date of birth of the

TSH-receptor blocking antibodies from mothers with autoimmune thyroid disease

Attending nursery school

child, mother and father

Height and weight of the child at birth

Antithyroid drugs

Exposition of the new-born during neonatal period:

Previous intellectual assessment

Actual height, weight of child, mother and father

Child negative life events

Contrast agents

Exposition to cold

Parenting stress

Organochlorides

Surgical hypothermia

Dysfunctional parenting

Head circumference of the child

Lithium

Delivery by forceps extraction

Cadmium

Household composition

Maternal smoking

TSH testing:

Nationality and origin of the child and the parents

Maternal alcohol consumption

Timing of blood sampling

TSH assay used

Parents related factors:

Maternal/paternal education and employment

Level of education

Household incomes

Household incomes

Marital status and custody

Maternal age at birth

Parity

Exposition of the new-born during neonatal period:

Exposure to iodine-containing antiseptics

Gravidity

Perinatal anoxia

Pre-pregnancy body mass index

Weight gain of the mother during pregnancy

Maternal diabetes during pregnancy

Maternal diabetes treatment during pregnancy

Maternal mental health disorders

Maternal poor social support

Marital discord