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Table 1 Study characteristics

From: Adherence influencing factors – a systematic review of systematic reviews

Study Search period Inclusion criteria*
Broekmans [11] Not limited – 12/2006 Adult patients with chronic non -malignant pain
   Adult patients with prescribed pain medication
   Original research
Daley [12] Not limited – 01/2012 Patients with Parkinson
   All ranges and duration of anti- parkinsonian treatments
   All age ranges
   Published in English
   Presenting quantitative/qualitative data
Oosterom-Calo [13] Not limited – 08/2010 50% heart failure patients
   Quantitative results were reported
   Studies of at least fair quality
   Evaluations of interventions were not the main purpose
   No descriptive study
   No review paper
   Published in English
Pasma [14] Not limited – 02/2011 Inflammatory arthritis patients
   Used a reproducible definition or validated instrument to measure adherence
   Provided a statistical measure to reflect the strength of the association between the determinant and adherence
   No letters, editorials, reviews, RCTs, case reports, qualitative studies and opinion articles
Schrijvers [15] Not reported – 15/2012 Haemophilia A or B
   Prophylactic treatment
   All age groups
Sinnott [16] 1946 – 09/2012 Participants received healthcare from a public insurance scheme
   Comparator group was the same population/similar population who either didn’t pay copayments or experienced no increase in copayment
   The intervention was copayment; either an increase in an existing copayment or the introduction of a copayment (no other types of cost-sharing, for example co-insurance)
   Studies included were randomised controlled trials, controlled before and after studies, interrupted time series designs, repeated measures designs, and cohort designs
Verbrugghe [17] NR Oral anti- cancer drugs
   Age ≥ 18
   Strong or moderate methodological quality
   Written in English, French, German or Dutch
   Original research articles published between 1990 and April 2012
   Studies not conducted in developing countries
   All study designs
  1. *Indication & medication marked bold.