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Table 2 Meta-analysis of the presence of high-risk HPV DNA in women with equivocal cervical cytology, by terminology group (ASCUS, Borderline Dyskaryosis or ASC-US)

From: Metaprop: a Stata command to perform meta-analysis of binomial data

Study ES [95% Conf. interval]   
ASCUS
Manos (1999) 0.395 0.364 0.426  
Bergeron (2000) 0.432 0.339 0.53  
Lytwyn (2000) 0.404 0.276 0.542  
Shlay (2000) 0.313 0.248 0.383  
Morin (2001) 0.292 0.245 0.342  
Solomon (2001) 0.568 0.547 0.588  
Kulasingam (2002) 0.511 0.45 0.572  
Pretorius (2002) 0.322 0.293 0.353  
Lonky (2003) 0.46 0.401 0.521  
Wensveen (2003) 0.453 0.371 0.537  
Rowe (2004) 0.44 0.38 0.501  
Andersson (2005) 0.442 0.305 0.587  
Palma (2005) 0.699 0.62 0.769  
Giovannelli (2005) 0.228 0.147 0.328  
Kendall (2005) 0.341 0.33 0.352  
Nieh (2005) 0.742 0.62 0.842  
Bergeron (2006) 0.444 0.422 0.467  
Kiatpongsan (2006) 0.389 0.288 0.497  
Monsonego (2006) 0.479 0.359 0.601  
Ronco (2007) 0.314 0.281 0.349  
Sub-total     
Random pooled ES 0.431 0.382 0.480  
BORDERLINE DYSKARYOS
Rebello (2001) 0.413 0.301 0.533  
Zielinski (2001) 0.347 0.284 0.415  
Cuzick (2003) 0.26 0.185 0.347  
Guyot (2003) 0.522 0.306 0.732  
Moss (2006) 0.456 0.44 0.473  
Cuschieri (2007) 0.605 0.532 0.675  
Sub-total     
Random pooled ES 0.428 0.341 0.516  
ASC-US
Bruner (2004) 0.269 0.182 0.371  
Kelly (2006) 0.725 0.583 0.841  
Ko (2006) 0.401 0.381 0.421  
Selvaggi (2006) 0.396 0.359 0.434  
Wright (2006) 0.341 0.315 0.368  
You (2007) 0.463 0.434 0.492  
Sub-total     
Random pooled ES 0.416 0.360 0.472  
Overall
Random pooled ES 0.428 0.395 0.461  
Test(s) of heterogeneity:
  Heterogeneity statistic Degrees of freedom p-value I 2
ASCUS 614.42 19 0.000 96.9%
BORDERLINE DYSKARYOS 53.58 5 0.000 90.7%
ASC-US 73.92 5 0.000 93.2%
Overall 785.77 31 0.000 96.1%
Random: Rest for heterogeneity between sub-groups:
  0.16 2 0.925  
** I 2: the variation in ES attributable to heterogeneity
Significance of test(s) of ES = 0
  ASCUS z = 17.22 p = 0.000  
  BORDERLINE    
  DYSKARYOS z = 9.58 p = 0.000  
  ASC-US z = 14.57 p = 0.000  
  Overall z = 25.31 p = 0.000  
  1. Output generated by the Stata procedure metaprop.