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Table 2 Comparison of socio-demographic, clinical, and laboratory profiles between patients with a new diagnosis of TB and those with retreatment TB in Yaoundé Central Hospital (2006–2013)

From: Characteristics of patients co-infected with HIV at the time of inpatient tuberculosis treatment initiation in Yaoundé, Cameroon: a tertiary care hospital-based cross-sectional study

 

Retreatment casesn = 40

New casesn = 297

p

Socio-demographic profile

   

Male

22 (55.0)

135 (45.5)

.256

Mean age, years

42.4 (8.6)

38.9 (10.4)

.042

Level of education

   

• No formal

5 (12.5)

43 (14.5)

.956

• Primary

5 (12.5)

43 (14.5)

 

• Secondary

18 (45.0)

131 (44.1)

 

• University

12 (30.0)

80 (26.9)

 

Residence

   

• Rural

4 (10.0)

32 (10.8)

1.0

• Urban

36 (90.0)

265 (89.2)

Matrimonial status

   

• Alone (single/divorced/widower)

17 (42.5)

165 (55.6)

.120

• Married

23 (57.5)

132 (44.4)

Clinical profile

   

Clinical presentation of TB

   

• PTB+ only

16 (40.0)

109 (36.7)

.975

• PTB- only

8 (20.0)

65 (22.6)

 

• EPTB only

14 (35.0)

105 (35.4)

 

• EPTB + PTB

2 (5.0)

16 (5.4)

 

Mean duration of known HIV infected, months

22.9 (33.6)

6.3 (15.2)

.004

Mean body weight, kg¥

53.2 (9.5)α

53.2 (10.4)β

.996

 

53.2 (9.4)

53.3 (10.5)

.941

Presence of another (excluding TB) AIDS opportunist infections (stage 2 – 4 of WHO classification of HIV infection)

4 (10.0)

49 (16.5)

.286

Presence of another comorbidities, no AIDS-no TB

8 (20.0)

32 (10.8)

.114

Co-trimoxazole prophylactic therapy

32 (80.0)

236 (79.8)

.937

Antiretroviral therapy

32 (80.0)

195 (65.7)

.069

Biological profile

   

Median CD4 count, cell/mm3 ¥

74 (19–169)

102 (34–181)£

.298

 

74 (19–169)

105 (35–184)

.238

Median white blood cell count, cell/mm3 ¥

5,750 (3,825-8,045)

5,000 (3,290-7,900)ε

.615

 

5,750 (3,825-8,045)

5,100 (3,260-8,000)

.538

Median hemoglobin level, g/dl¥

9 (7–10)

8 (7–10)ε

.846

 

9 (7–10)

8 (7–10)

.802

  1. Data are mean (standard deviation), n (%) and median (interquartile range).
  2. Missing data:α2, β34, £28, and ε18.
  3. PTB+ and PTB-: smear -positive and –negative pulmonary TB.
  4. EPTB: Extra pulmonary TB.
  5. ¥The row under this variable presents sensitivity analysis after multiple imputation of missing data.