Skip to main content

Table 2 methodology of the meta-analyses on the effect of intense sweeteners on body composition.

From: Review of the nutritional benefits and risks related to intense sweeteners

First Author, year of publication (reference) Search date Database used Population Study design Main findings Heterogeneity Publication bias
de la Hunty, 2006 (ref 9) Not clear Not clear Healthy adults RCT (N = 9) Non-significant effect size of 0.221 (0.000 to 0.443) standard deviation of weight loss Not assessed Not assessed
Miller, 2014 (ref 16) 16 September 2013 PubMed + manual search Healthy adults and children RCT (N = 15)
Prospective study (N = 9)
1. RCT:   No evidence of publication bias (Egger’s regression test)
- on weight: -0.80 kg (–1.17 to –0.43) I2 61 %
- on body mass index: –0.24 kg/m2 (–0.41 to –0.07) I2 0 %
2. Prospective studies  
- on weight: 0.02 kg (–0.01 to –0.06) I2 92 %
- on body mass index: 0.03 kg/m2 (0.01 to 0.06) I2 53 %