From: Review of the nutritional benefits and risks related to intense sweeteners
First Author, year of publication (reference) | Search date | Database used | Population | Study design | Main findings | Heterogeneity | Publication bias |
---|---|---|---|---|---|---|---|
de la Hunty, 2006 (ref 9) | Not clear | Not clear | Healthy adults | RCT (N = 9) | Non-significant effect size of 0.221 (0.000 to 0.443) standard deviation of weight loss | Not assessed | Not assessed |
Miller, 2014 (ref 16) | 16 September 2013 | PubMed + manual search | Healthy adults and children | RCT (N = 15) Prospective study (N = 9) | 1. RCT: |  | No evidence of publication bias (Egger’s regression test) |
- on weight: -0.80 kg (–1.17 to –0.43) | I2 61 % | ||||||
- on body mass index: –0.24 kg/m2 (–0.41 to –0.07) | I2 0 % | ||||||
2. Prospective studies | Â | ||||||
- on weight: 0.02 kg (–0.01 to –0.06) | I2 92 % | ||||||
- on body mass index: 0.03Â kg/m2 (0.01 to 0.06) | I2 53Â % |