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Table 1 Factors associated with unsuccessful tuberculosis treatment outcome, São Paulo-state, Brazil, 2011–2015

From: Impact of alcohol disorder and the use of illicit drugs on tuberculosis treatment outcomes: a retrospective cohort study

Characteristics

Total

Incidence of unsuccessful outcome of tuberculosis treatment

Crude RR (95% CI)a

Adjusted RR (95% CI)a

No.

%

Overall

77,212

13,300

17

  

Alcohol and illicit drug

 Neither

60,107

8607

14.3

1

1

 Only alcohol disorder

7487

1765

23.6

1.65 (1.57–1.72)

1.48 (1.4–1.56)

 Only drug use

5199

1472

28.3

1.98 (1.89–2.07)

2.1 (1.98–2.21)

 Alcohol disorder and drug use

4418

1456

33

2.3 (2.2–2.41)

2.09 (1.97–2.21)

Sex

 Female

22,498

3102

13.8

1

1

 Male

54,714

10,198

18.6

1.35 (1.3–1.4)

1.27 (1.22–1.32)

Age (years)

 15–34

36,080

5370

14.9

1

1

 34–49

21,681

4068

18.8

1.26 (1.21–1.31)

0.99 (0.94–1.03)

 50 and more

19,451

3862

19.9

1.33 (1.28–1.38)

1.23 (1.18–1.29)

Race

 Non-black

35,707

5727

16

1

1

 Black

33,135

5951

18

1.12 (1.08–1.16)

1.13 (1.09–1.17)

HIV

 No

69,973

10,582

15.1

1

1

 Yes

7239

2718

37.5

2.48 (2.4–2.57)

2.16 (2.07–2.26)

Clinical form

 Pulmonary

65,271

11,364

17.4

1

1

 Extrapulmonary

11,903

1899

16

0.92 (0.88–0.96)

0.86 (0.82–0.9)

Prison

 No

68,228

12,608

18.5

1

1

 Yes

8984

692

7.7

0.42 (0.39–0.45)

0.51 (0.47–0.56)

Homeless

 No

75,218

12,278

16.3

1

1

 Yes

1993

1022

51.3

3.14 (3–3.29)

2 (1.89–2.13)

Directly observed treatment

 No

16,791

4237

25.2

1

1

 Yes

54,940

7198

13.1

0.52 (0.5–0.54)

0.55 (0.53–0.57)

  1. RR relative risk, 95% CI 95% confidence interval
  2. aBoldface indicates statistical significance (p < 0.05)