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Table 3 Adjusted fraction of unsuccessful outcomes in a population of TB patients that was attributable to alcohol disorder and illicit drug use (PAF%), São Paulo-state, Brazil, 2011–2015

From: Impact of alcohol disorder and the use of illicit drugs on tuberculosis treatment outcomes: a retrospective cohort study

Alcohol and illicit drug

Main analysisa

PAF (95% CI)

Model 1a,b

PAF (95% CI)

Model 2a,b

PAF (95% CI)

Neither

 Only alcohol disorder

4.3 (3.8–4.8)

4.3 (3.8–4.8)

3.7 (3.3–4.2)

 Only drug use

5.8 (5.5–6.1)

5.8 (5.5–6.1)

5 (4.8–5.3)

 Alcohol disorder and drug use

5.7 (5.4–6.0)

5.7 (5.4–6)

5 (4.7–5.3)

 Total

15.8 (15.0–16.5)

15.8 (15.1–16.6)

13.8 (13.1–14.5)

  1. PAF Population Attributable Fraction, 95% CI 95% confidence interval
  2. aEstimates based on relative risks adjusted by sex, age, race, HIV, clinical form of TB, prison, homeless and directly observed treatment
  3. bModel 1- unobserved treatment outcomes set to successful; model 2- unobserved treatment outcomes set to unsuccessful