Table 3 Factors associated with major birth defects: unadjusted and adjusted odds ratio
| Â | With major birth defect | Without major birth defect | Unadjusted | Adjusteda | ||||
|---|---|---|---|---|---|---|---|---|
Variável | N = 140 (%) | N = 30,589 (%) | OR | CI 95% | p value | OR | CI 95% | p value |
Maternal education | ||||||||
 Up to 7 years of study | 41 (30) | 6.739 (22) | 1.46b | 1.01–2.10 | 0.0414 | 1.58b | 1.07–2.33 | 0.0213 |
 More than 7 years of study | 99 (70) | 23.792 (78) | 1.00 | – | – | – | – | – |
Maternal race | ||||||||
 White | 92 (65.7) | 19.118 (62.9) | 1.00 | – | – | – | – | – |
 Other | 48 (34.3) | 11.297 (37.1) | 0.88 | 0.62–1.25 | 0.4854 | 0.82 | 0.57–1.19 | 0.3078 |
Country of residence | ||||||||
 Brazil | 129 (92.1) | 28.894 (94.5) | 1.00 | – | – | – | – | – |
 Others | 11 (7.9) | 1.695 (5.5) | 1.45 | 0.78–2.69 | 0.2392 | 1.11 | 0.54–2.29 | 0.7611 |
Maternal parity | ||||||||
 Primiparous | 59 (42) | 11.862 (39) | 1.00 | – | – | – | – | – |
 Multiparous | 81 (58) | 18.596 (61) | 0.87 | 0.62–1.22 | 0.4392 | 0.82 | 0.58–1.18 | 0.2981 |
Onset of prenatal care | ||||||||
 First trimester | 104 (80) | 24.974 (84) | 1.00 | – | – | – | – | – |
 After the first trimester | 27 (20) | 4.782 (16) | 1.35 | 0.88–2.07 | 0.1590 | 1.29 | 0.83–1.99 | 0.2450 |