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Table 4 Association of eating quickly with AST/ALT ratio < 1 among participants with ALT > 40 or not (Japan, from April 2013 to March 2014)

From: Eating quickly is associated with a low aspartate aminotransferase to alanine aminotransferase ratio in middle-aged adults: a large-scale cross-sectional survey in Japan

  

Not eating quickly group

Eating quickly group

Model 1

Model 2

Model 3

    

OR (95%CI)

p value

OR (95%CI)

p value

OR (95%CI)

p value

Men

 ALT > 40

 

(n = 17,113)

(n = 9502)

      
 

AST/ALT ratio < 1, n (%)

15,338 (89.6)

8985 (94.6)

2.01 (1.81–2.23)

<  0.001

1.49 (1.33–1.66)

<  0.001

1.18 (1.05–1.33)

0.004

 

AST/ALT ratio ≥ 1, n (%)

1775 (10.4)

517 (5.4)

1.00

 

1.00

 

1.00

 

 ALT ≤40

 

(n = 114,878)

(n = 44,031)

      
 

AST/ALT ratio < 1, n (%)

42,952 (37.4)

20,322 (46.2)

1.44 (1.40–1.47)

<  0.001

1.38 (1.35–1.41)

<  0.001

1.09 (1.06–1.12)

<  0.001

 

AST/ALT ratio ≥ 1, n (%)

71,926 (62.6)

23,709 (53.8)

1.00

 

1.00

 

1.00

 

Women

 ALT > 40

 

(n = 3127)

(n = 1213)

      
 

AST/ALT ratio < 1, n (%)

2802 (89.6)

1114 (91.8)

1.30 (1.03–1.65)

0.027

1.18 (0.92–1.51)

0.185

1.06 (0.83–1.36)

0.638

 

AST/ALT ratio ≥ 1, n (%)

325 (10.4)

99 (8.2)

1.00

 

1.00

 

1.00

 

 ALT ≤40

 

(n = 72,260)

(n = 20,949)

      
 

AST/ALT ratio < 1, n (%)

10,657 (14.7)

3926 (18.7)

1.33 (1.28–1.39)

<  0.001

1.35 (1.30–1.41)

<  0.001

1.11 (1.07–1.16)

<  0.001

 

AST/ALT ratio ≥ 1, n (%)

61,603 (85.3)

17,023 (81.3)

1.00

 

1.00

 

1.00

 
  1. BMI body mass index, AST aspartate amino transferase, ALT alanine amino transferase
  2. γ-GTP, γ-glutamyl transpeptidase; OR, odds ratio; CI, confidence interval
  3. Model 1: No adjustment
  4. Model 2: Adjusted for age, γ-GTP, smoking status, alcohol intake, physical activity
  5. Moedl 3: Adjusted for age, BMI, γ-GTP, smoking status, alcohol intake, physical activity