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Table 2 Key steps in describing disease epidemiology for burden of disease studies [16]

From: Reflections on key methodological decisions in national burden of disease assessments

• What is the current knowledge on the disease being studied?
• What are the limitations of the current knowledge on the disease being studied?
• What are the relevant data available on the natural history of the disease and its disabling sequelae? (prevalence, incidence, duration, age of onset, remission rate, and mortality rate, level of severity and duration from disease onset to disabling sequela)?
• If there are no precise data, is there at least a general consensus amongst disease experts?