Table 4 Example of a disease specific and generic description of moderate to severe depression, based on Kruijshaar et al. 2005 [62]

This person experiences one or more depressive episodes within a year. During these periods they go through permanent feelings of sadness or emptiness and a permanent loss of interest or pleasure in nearly all activities. He/she has problems eating and/or sleeping and feel worthless or guilty. He/she may have thoughts of death.

This person has some problems with performing usual activities, feeling tired, moderate anxiety or depression, some cognitive impairments.