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Table 1 Most significant change evaluations of public health research interventions

From: How beneficiaries see complex health interventions: a practice review of the Most Significant Change in ten countries

Name of project Country Intervention Study design Intervention participants Number of stories Sample Recording method Analysis
1. AIDS prevention for the choice disabled
(2008–2012)
Botswana Namibia and Eswatini Structural intervention for primary HIV prevention among vulnerable young women Cluster randomized controlled trial 75 communities (25 in each country) randomized to one or more of three interventions or control 89 BVV
76 FW
Purposive by country Notes by story collectors Hierarchical
Deductive thematic
2. Proyecto Buena Semilla
(2013–2019)
Guatemala Women’s Circles to empower women as agents of change in their lives, families and communities Parallel group non-randomized pilot study > 230 in deliberative dialogue
> 550 in Women’s Circles
> 60 community health workers and traditional midwives
207 Purposive Audio-recording by trained interviewer Deductive and inductive thematic
3. Video edutainment & maternal outcomes in Toro, Nigeria
(2015–2020)
Nigeria Universal home visits to pregnant women and their spouses Cluster randomized controlled trial in stepped wedge design Six wards in one local government authority. 33,000 households with population of 260,000. 23 women
21 men
14 visitors
6 govt officers
64 total
Purposive Notes by story collectors Hierarchical
Deductive and inductive thematic
4. Inter-ministerial National Structural Intervention Trial
2014–2018
Botswana Structural intervention to reduce HIV infections, particularly among
marginalized young women
Cluster randomized controlled trial Five intervention districts, total population of about 275,000 117 young women Purposive Notes by story collectors Inductive thematic
5. Camino Verde dengue trial
(2008–2015)
Mexico & Nicaragua Community mobilization for dengue prevention Cluster randomized controlled trial 18,838 households in Nicaragua and Mexico with a total population of 85,182 residents 16 facilitators Purposive Self-recorded Grounded theory; discourse analysis
6. Safe birth in cultural safety
(2015–2017)
Mexico Support for traditional midwives including stipend, apprentices, cultural brokers Cluster randomized controlled trial 8000 households
> 28 traditional midwives
> 29 midwife apprentices
> 17 intercultural brokers
84 Purposive Notes by story collectors Reflexive thematic
7. Pilot cultural safety training
(2016)
Colombia Participation in community-based cultural safety training program Qualitative descriptive study 13 final-year medical students 13 Universal Self-recorded Inductive thematic
8. Training in evidence-based planning
(2015–2016)
Botswana: participants from 14 SADC countries Participation in course on evidence-based planning, including session on MSC technique Course practical 64 Health planners and researchers (4 classes) 64 Universal Notes by fellow students in pairs Inductive thematic
9. Safe birth in post-conflict setting (2019–2020) Uganda Co-design of safe-birth intervention Cross sectional study 3 service providers, 3 men, 3 women, 2 female youth, 3 male youth, 3 CHWs, 3 traditional midwives 20 Purposive Notes by male and females story collectors Inductive thematic
10. McGill Participatory Research course
(2016–2018)
Canada Course on Participatory Research, including session on MSC Course practical 75 graduate students (3 classes) 75 Universal Self-recorded Inductive and deductive thematic
  1. SADC Southern Africa Development Community. Countries represented on the courses: Botswana, Lesotho, Malawi, Mauritius, Namibia, Seychelles, Swaziland, Tanzania, Zambia and Zimbabwe (Anglophone); Democratic Republic of Congo and Madagascar (Francophone); Angola, and Mozambique (Lusophone)
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