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Table 1 Patient demographics (mean, standard deviation, number, frequency and p-value) of the total study population (n = 182) and per country (the Netherlands, France, the United Kingdom, Spain and elsewhere (Germany or Italy)), 2019

From: Health-related quality of life of multiple sclerosis patients: a European multi-country study

 

Total

(n = 182)

The Netherlands (n = 88)

France

(n = 58)

The United Kingdom (n = 15)

Spain

(n = 10)

Elsewhere (n = 11)

P-value

Age, mean (±SD)

43.09 (10.53)

43.97 (10.27)

40.88 (10.57)

47.6 (9.39)

42.90 (11.37)

41.73 (12.08)

0.237a

Age at diagnosis, mean (±SD)

34.12 (10.36)

35.18 (10.3)

31.22 (9.53)

41.6 (10.17)

31.67 (11.04)

32.75 (9.84)

0.006a*

Time since diagnosis, mean (±SD)c

8.97 (7.8)

8.78 (7.33)

9.66 (8.61)

6 (4.31)

9.8 (9.5)

10.18 (927)

0.834a

Gender, n (%)

      

0.746b

 Male

39 (21.43)

21 (23.86)

9 (15.52)

3 (20.00)

3 (33.00)

3 (27.27)

 

 Female

142 (78.02)

66 (75.00)

49 (84.48)

12 (80.00)

7 (70.00)

8 (72.73)

 

 Prefer not to say

1 (0.55)

1 (1.14)

     

Type of MS, n (%)

      

0.649b

 CIS

2 (1.10)

 

2 (3.45)

    

 RRMS

146 (80.22)

70 (79.55)

47 (81.03)

10 (66.67)

9 (90.00)

10 (90.91)

 

 PPMS

17 (9.34)

10 (11.36)

4 (6.90)

3 (20.00)

1 (10.00)

1 (9.09)

 

 SPMS

17 (9.34)

8 (9.09)

5 (8.62)

2 (13.33)

   

EDSS, n (%)

      

0.070b

 EDSS <= 2.5

45 (24.73)

12 (13.64)

20 (34.48)

3 (20.00)

6 (60.00)

4 (36.36)

 

 EDSS 3–6.5

35 (19.23)

15 (17.05)

12 (20.69)

4 (26.67)

2 (20.00)

2 (18.18)

 

 EDSS > = 6

26 (14.29)

14 (15.91)

6 (10.34)

6 (40.00)

2 (20.00)

  

 Unknown

58 (31.87)

30 (34.09)

20 (34.48)

2 (13.33)

 

4 (36.36)

 

 Missing

18 (9.89)

17 (19.32)

   

1 (9.09)

 

Marital status, n (%)

      

0.986b

 Single

36 (19.78)

17 (19.32)

13 (21.41)

3 (20.00)

1 (10.00)

2 (18.18)

 

 Partnered

42 (23.08)

21 (23.86)

13 (21.41)

5 (33.33)

2 (20.00)

1 (9.09)

 

 Married

96 (52.75)

44 (50.00)

30 (51.72)

7 (46.67)

7 (70.00)

8 (72.73)

 

 Divorced

7 (3.85)

5 (5.68)

2 (3.45)

    

 Widowed

1 (0.55)

1 (1.14)

     

Educational level, n (%)

      

0.000b

 Primary education

1 (0.55)

   

1 (10.00)

  

 Secondary education

13 (7.14)

9 (10.23)

 

3 (20.00)

 

1 (9.09)

 

 Vocational/technical education

67 (36.82)

44 (50.00)

14 (24.14)

4 (26.67)

3 (30.00)

2 (18.18)

 

 University

95 (52.20)

35 (39.77)

41 (70.69)

6 (40.00)

5 (50.00)

8 (72.73)

 

 Other

6 (3.30)

 

3 (5.17)

2 (13.33)

1 (10.00)

  

Nationality, n (%)

 British

14 (7.69)

  

14 (93.33)

   

 French

59 (32.42)

 

57 (98.28)

  

2 (18.18)

 

 Dutch

91 (50.00)

87 (98.86)

1 (1.72)

  

3 (27.27)

 

 Spanish

9 (4.95)

   

9 (90.00)

  

 Other

9 (4.95)

1 (1.14)

 

1 (6.67)

1 (10.00)

6 (54.55)

 
  1. MS Multiple sclerosis, CIS Clinically isolated syndrome, RRMS Relapsing-remitting MS, PPMS Primary progressive MS, SPMS Secondary progressive MS, EDSS Expanded Disability Status Scale, a: Kruskal-Wallis test, b: Fisher’s exact test, c: Time since diagnosis was calculated by subtracting the age at diagnosis from the current age, *Significant difference in mean age at diagnosis between France and the United Kingdom (p = 0.002) using Dunn’s test and Bonferroni correction