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Table 3 Agreement analyses (kappa statistic) for different patient subgroups (grouped based on patient and tumor characteristics), comparing principal cause of death from death certificates and medical files

From: Cause of death for patients with breast cancer: discordance between death certificates and medical files, and impact on survival estimates

Category Subgroups Number of patients alive Number of deceased patients (FU 31-12-2016) Kappa statistic Spearman’s correlation coefficient and p-value
Age <40 years 177 11 NDa Rho= -0.7
P-value= 0.23
40-49 525 37 0.64
50-59 736 42 0.83
60-69 649 60 0.73
70-79 334 89 0.54
≥80 87 115 0.50
Year of diagnosis 2009 393 96 0.77 Rho= -0.26
P-value= 0.67
2010 379 69 0.59
2011 398 70 0.71
2012 429 54 0.67
2013 472 28 0.78
2014 437 37 0.54
Stage at diagnosis Stage 0 46 1 NDa Rho= -0.8
P-value= 0.33
Stage I 1019 44 0.76
Stage II 1053 121 0.69
Stage III 288 69 0.75
Stage IV 56 102 0.35
Stage unknownb 46 17 0.43
Grade of tumor Grade 1 301 18 NDa NDc
Grade 2 1223 155 0.58
Grade 3 960 166 0.81
Grade unknownb 24 15 0.86
Multiple tumors Yes 94 35 0.66 NDc
No 2414 319 0.69
  1. aNot defined due to events within subgroup being too small
  2. b subgroups with unknown stage or grade were not included in Spearman analyses
  3. cnot defined due to subgroup without ranked variables