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Table 1 Basic information of the studies included in the meta-analysis

From: Seroprevalence of coxsackievirus A16 antibody among people of various age groups: a systematic review and meta-analysis

First author

Publication year

Country

Location

Sample size

No. positive

Seroprevalence rate (%)

Assay method

Positive threshold

Age range

Group factors

AHRQ scores

Cheng [14]

2016

China

Jiangsu

420

125

29.76

NTA

1:8

0–15 yrs

Age, gender

8

Han [15]

2014

China

Shandong

1000

786

78.60

ELISA

OD450

0–31 yrs

Age, gender

8

Mao [16]

2009

China

Henan

337

123

36.50

NTA

1:8

7–30 mons

Age

7

Song [17]

2020

China

Tianjin

171

107

62.57

NTA

1:8

0–35 yrs

Age, gender

7

Ang [18]

2015

Singapore

Singapore

700

424

60.57

NTA

1:8

1–17 yrs

Age, gender, ethnic

9

Zhu [19]

2012

China

Jiangsu

1530

1024

66.93

NTA

1:8

all ages

Age

7

Lerdsamran [20]

2018

Thailand

Thailand

696

438

62.93

NTA

1:8

6–18 yrs

Age, gender

8

Rabenau [21]

2010

Germany

Germany

1378

989

71.77

NTA

1:8

all ages

Age, gender

8

Wang [22]

2016

China

Shandong

391

230

58.82

NTA

1:8

all ages

Age, gender

9

Wang [23]

2014

China

Jiangsu

715

400

55.94

NTA

1:8

20–50 yrs

Age, gender

9

Li [24]

2013

China

Guangdong

900

390

43.33

NTA

1:8

1–9 yrs

Age, gender

9

Zhu [25]

2010

China

Mixed

515

128

24.85

NTA

1:8

1–5 yrs

Age

8

Zhu [26]

2018

China

Fujian

230

176

76.52

NTA

1:8

all ages

Age, gender

8

Li [27]

2017

China

Tianjin

420

125

29.76

NTA

1:8

all ages

Age, gender

8