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Table 2 Numbers, calculated rates, extreme values, significance and E-Values for THC

From: Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer incidence 2003–2017: part 2 – categorical bivariate analysis and attributable fractions

No. Cancer Numbers Calculated Rates Significance E-Values
Highest Quintile Cancer Count Highest Quintile Not Cancer Count Lowest Quintile Cancer Count Lowest Quintile Not Cancer Count Highest Quintile State Cancer Rate Lowest Quitile State Cancer Rate Rate Ratio (C.I.) Atrributable Fraction in the Exposed (C.I.) Population Attributable Risk (C.I.) Chi Squared P-Value E-Value - Point Estimate E-Value - Lower Bound
1 Melanoma 306,838 830,574,345 150,253 881,048,930 36.9429 17.0539 2.1662 (2.1529, 2.1797) 0.5383 (0.5354, 0.5411) 0.3613 (0.3587, 0.364) 63,311.55 2.2E-320 3.75 3.73
2 Thyroid 151,334 830,729,849 107,883 881,091,300 18.2170 12.2442 1.4878 (1.4762, 1.4995) 0.3278 (0.3226, 0.3331) 0.1914 (0.1877, 0.1951) 10,071.61 2.2E-320 2.34 2.31
3 Liver 111,574 830,769,609 82,274 881,116,909 13.4302 9.3375 1.4383 (1.4254, 1.4513) 0.3047 (0.2984, 0.3109) 0.1754 (0.1711, 0.1796) 6324.55 2.2E-320 2.23 2.20
4 AML 52,732 830,828,451 48,622 881,150,561 6.3469 5.5180 1.1502 (1.1361, 1.1645) 0.1306 (0.1198, 0.1412) 0.0679 (0.0619, 0.0739) 496.25 3.11E-110 1.57 1.53
5 ALL 16,966 783,231,729 12,435 647,668,506 2.1662 1.9200 1.1282 (1.1024, 1.1546) 0.1137 (0.0929, 0.1339) 0.0656 (0.053, 0.078) 104.57 7.65E-25 1.51 1.44
6 Pancreas 145,673 830,735,510 139,408 881,059,775 17.5354 15.8228 1.1082 (1.1001, 1.1164) 0.0977 (0.091, 0.1043) 0.0499 (0.0463, 0.0535) 752.96 4.57E-166 1.45 1.43
7 Myeloma 69,035 830,812,148 68,850 881,130,333 8.3093 7.8138 1.0634 (1.0522, 1.0747) 0.0596 (0.0496, 0.0695) 0.0299 (0.0247, 0.035) 130.35 1.73E-30 1.32 1.29
8 CML 20,771 817,987,548 20,592 869,335,404 2.5393 2.3687 1.072 (1.0515, 1.0929) 0.0672 (0.049, 0.085) 0.0337 (0.0243, 0.043) 50.02 1.52E-12 1.35 1.28
9 Breast 725,943 830,155,240 737,913 880,461,270 87.4467 83.8098 1.0434 (1.04, 1.0468) 0.0416 (0.0384, 0.0447) 0.0206 (0.019, 0.0222) 659.85 8.06E-146 1.26 1.24
10 Oropharynx 131,976 830,749,207 137,604 881,061,579 15.8864 15.6180 1.0172 (1.0095, 1.0249) 0.0169 (0.0094, 0.0243) 0.0083 (0.0046, 0.0119) 19.56 9.76E-06 1.15 1.11
11 Stomach 76,462 830,804,721 79,792 881,119,391 9.2034 9.0558 1.0163 (1.0063, 1.0264) 0.016 (0.0062, 0.0257) 0.0078 (0.003, 0.0127) 10.21 0.0014 1.15 1.09
12 Kidney 175,942 830,705,241 186,020 881,013,163 21.1798 21.1143 1.0031 (0.9966, 1.0097) 0.0031 (−0.0034, 0.0096) 0.0015 (− 0.0017, 0.0047) 0.87 0.3517 1.06 1.00
13 Testis 99,195 3,340,448,691 9779 329,626,401 2.9695 2.9667 1.001 (0.9804, 1.022) 9E-04 (−0.02, 0.0215) 9E-04 (− 0.0182, 0.0196) 0.01 0.9286 1.03 1.00
14 Vulva.&.Vagina 30,270 818,877,375 32,443 869,064,024 3.6965 3.7331 0.9902 (0.9748, 1.0058) − 0.0099 (− 0.0258, 0.0058) −0.0048 (− 0.0124, 0.0028) 1.52 0.1516 1.11
15 Penis 5118 705,633,086 5593 741,467,258 0.7253 0.7543 0.9615 (0.9258, 0.9987) −0.04 (− 0.0802, − 0.0013) − 0.0191 (− 0.0377, −8E-04) 4.11 0.0252 1.24
16 NH_Lymphoma 205,403 830,675,780 221,653 880,977,530 24.7272 25.1599 0.9828 (0.9769, 0.9887) −0.0175 (− 0.0236, − 0.0114) −0.0084 (− 0.0113, − 0.0055) 32.07 7.65E-09 1.15
17 Bladder 224,188 830,656,995 242,360 880,956,823 26.9892 27.5110 0.981 (0.9754, 0.9867) −0.0193 (− 0.0252, − 0.0135) −0.0093 (− 0.0121, − 0.0065) 42.69 3.28E-11 1.16
18 Hodgkins 22,119 830,859,064 25,028 881,174,155 2.6622 2.8403 0.9373 (0.9205, 0.9544) −0.0669 (− 0.0864, − 0.0478) −0.0314 (− 0.0402, − 0.0227) 49.26 1.14E-12 1.33
19 Brain 62,587 830,818,596 70,422 881,128,761 7.5332 7.9922 0.9426 (0.9325, 0.9528) −0.0609 (− 0.0724, − 0.0496) −0.0287 (− 0.0339, − 0.0235) 115.98 2.42E-27 1.32
20 CLL 56,985 830,824,198 64,593 881,134,590 6.8589 7.3307 0.9356 (0.9252, 0.9462) −0.0688 (− 0.0809, − 0.0568) −0.0322 (− 0.0377, − 0.0268) 134.03 2.71E-31 1.34
21 Kaposi 4637 479,415,678 3147 235,124,390 0.9672 1.3384 0.7226 (0.6907, 0.7561) −0.3838 (− 0.4479, − 0.3226) −0.2286 (− 0.2622, − 0.1959) 199.56 1.31E-45 2.11
22 Esophagus 49,631 830,831,552 57,097 872,338,233 5.9737 6.5453 0.9127 (0.9018, 0.9237) −0.0957 (− 0.1089, − 0.0826) −0.0445 (− 0.0504, − 0.0387) 221.88 1.77E-50 1.42
23 Cervix 33,197 830,847,986 43,411 881,155,772 3.9956 4.9266 0.811 (0.7995, 0.8227) −0.233 (− 0.2508, − 0.2155) −0.101 (− 0.1078, − 0.0942) 828.36 1.84E-182 1.77
24 Ovary 61,447 830,819,736 76,403 881,122,780 7.3959 8.6711 0.8529 (0.8439, 0.8621) −0.1724 (− 0.1849, − 0.16) −0.0768 (− 0.082, − 0.0718) 863.42 4.40E-190 1.62
25 All_Cancer 4,669,820 826,211,363 5,337,600 875,861,583 565.2089 609.4114 0.9275 (0.9263, 0.9286) −0.0777 (− 0.0791, − 0.0764) − 0.0363 (− 0.0369, − 0.0357) 14,046.15 2.2E-320 1.37
26 Colorectal 378,062 830,503,121 545,289 880,653,894 45.5220 61.9186 0.7352 (0.7321, 0.7382) −0.36 (− 0.3656, − 0.3543) −0.1474 (− 0.1493, − 0.1454) 21,284.10 2.2E-320 2.06
27 Lung 577,790 830,303,393 791,383 880,407,800 69.5878 89.8882 0.7742 (0.7715, 0.7768) −0.2915 (− 0.2958, − 0.2871) −0.123 (− 0.1246, − 0.1214) 21,985.04 2.2E-320 1.90
28 Prostate 483,411 830,397,772 723,959 880,475,224 58.2144 82.2237 0.708 (0.7054, 0.7106) − 0.4121 (− 0.4172, − 0.407) −0.165 (− 0.1667, − 0.1633) 34,883.31 2.2E-320 2.17