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Table 3 Numbers, calculated rates, extreme values, significance and E-Values for cannabidiol

From: Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer incidence 2003–2017: part 2 – categorical bivariate analysis and attributable fractions

No. Cancer Numbers Calculated Rates Significance e-Values
Highest Quintile Cancer Count Highest Quintile Not Cancer Count Lowest Quintile Cancer Count Lowest Quintile Not Cancer Count Highest Quintile State Cancer Rate Lowest Quitile State Cancer Rate Rate Ratio (C.I.) Atrributable Fraction in the Exposed (C.I.) Population Attributable Risk (C.I.) Chi Squared P-Value E-Value - Point Estimate E-Value - Lower Bound
1 Prostate 628,831 755,360,319 535,377 898,438,080 83.2491 59.5897 1.397 (1.392, 1.4021) 0.284 (0.2814, 0.2866) 0.1534 (0.1517, 0.1551) 32,606.52 2.2E-320 2.14 2.13
2 Melanoma 214,839 755,774,311 186,976 898,786,481 28.4263 20.8032 1.3664 (1.358, 1.3749) 0.2681 (0.2636, 0.2726) 0.1434 (0.1405, 0.1462) 9821.70 2.2E-320 2.07 2.06
3 Kaposi 5120 402,044,093 1906 201,510,515 1.2735 0.9459 1.3464 (1.2774, 1.4191) 0.2573 (0.2172, 0.2953) 0.1875 (0.1557, 0.218) 123.78 4.75E-29 2.03 1.87
4 Ovary 66,781 755,922,369 64,493 898,908,964 8.8344 7.1746 1.2313 (1.2181, 1.2447) 0.1879 (0.179, 0.1966) 0.0956 (0.0906, 0.1005) 1425.88 2.49E-312 1.77 1.73
5 Bladder 226,085 755,763,065 227,293 898,746,164 29.9148 25.2900 1.1829 (1.176, 1.1898) 0.1546 (0.1496, 0.1595) 0.0771 (0.0744, 0.0797) 3203.50 2.2E-320 1.65 1.63
6 Colorectal 433,034 755,556,116 437,615 898,535,842 57.3133 48.7031 1.1768 (1.1719, 1.1817) 0.1502 (0.1466, 0.1537) 0.0747 (0.0727, 0.0766) 5777.63 2.2E-320 1.63 1.62
7 Stomach 75,022 755,914,128 76,657 898,896,800 9.9247 8.5279 1.1638 (1.1521, 1.1756) 0.1407 (0.132, 0.1493) 0.0696 (0.065, 0.0742) 873.91 2.30E-192 1.60 1.57
8 Hodgkins 22,571 755,966,579 24,142 898,949,315 2.9857 2.6856 1.1118 (1.0918, 1.1321) 0.1005 (0.084, 0.1167) 0.0486 (0.0402, 0.0569) 131.04 1.22E-30 1.46 1.41
9 Esophagus 48,540 755,940,610 52,144 885,656,175 6.4211 5.8876 1.0906 (1.0772, 1.1042) 0.0831 (0.0717, 0.0943) 0.0401 (0.0343, 0.0458) 189.27 2.31E-43 1.40 1.37
10 NH_Lymphoma 197,820 755,791,330 217,228 898,756,229 26.1739 24.1698 1.0829 (1.0763, 1.0895) 0.0765 (0.0709, 0.0822) 0.0365 (0.0337, 0.0393) 657.13 3.15E-145 1.38 1.36
11 All_Cancer 4,624,006 751,365,144 5,120,676 893,852,781 615.4140 572.8769 1.0743 (1.0729, 1.0756) 0.0687 (0.0676, 0.0699) 0.0326 (0.032, 0.0332) 12,396.64 2.2E-320 1.36 1.35
12 Brain 61,078 755,928,072 67,967 898,905,490 8.0799 7.5611 1.0686 (1.057, 1.0804) 0.0642 (0.0539, 0.0744) 0.0304 (0.0254, 0.0354) 141.71 5.67E-33 1.34 1.30
13 Lung 613,629 755,375,521 692,710 898,280,747 81.2350 77.1151 1.0534 (1.0498, 1.0571) 0.0507 (0.0474, 0.0539) 0.0238 (0.0222, 0.0254) 880.93 6.87E-194 1.29 1.28
14 CLL 57,004 755,932,146 65,126 898,908,331 7.5409 7.2450 1.0408 (1.0292, 1.0526) 0.0392 (0.0284, 0.05) 0.0183 (0.0131, 0.0234) 48.70 2.98E-12 1.25 1.20
15 Breast 663,949 755,325,201 765,406 898,208,051 87.9024 85.2148 1.0315 (1.0282, 1.0349) 0.0305 (0.0274, 0.0337) 0.0142 (0.0127, 0.0157) 342.56 1.52E-12 1.21 1.20
16 ALL 14,432 706,424,364 14,542 698,662,054 2.0430 2.0814 0.9815 (0.9592, 1.0044) −0.0188 (− 0.0426, 0.0044) − 0.0094 (− 0.021, 0.0021) 2.52 0.1126 1.16
17 Cervix 32,826 755,956,324 40,390 898,933,067 4.3423 4.4931 0.9664 (0.9525, 0.9806) − 0.0347 (− 0.0499, − 0.0198) − 0.0156 (− 0.0222, − 0.009) 21.10 4.35E-06 1.22
18 Testis 100,691 3,454,899,465 17,319 568,210,402 2.9144 3.0480 0.9562 (0.9409, 0.9717) − 0.0458 (− 0.0628, − 0.0291) −0.0391 (− 0.0535, − 0.0249) 29.67 5.13E-08 1.26
19 Pancreas 126,380 755,862,770 158,175 898,815,282 16.7200 17.5982 0.9501 (0.9431, 0.9571) −0.0525 (− 0.0603, − 0.0448) −0.0233 (− 0.0267, − 0.02) 184.10 8.88E-77 1.29
20 Penis 4195 566,547,406 6196 792,274,553 0.7404 0.7821 0.9468 (0.9104, 0.9846) −0.0562 (− 0.0984, − 0.0156) −0.0227 (− 0.039, − 0.0066) 7.48 0.0063 1.30
21 Vulva.&.Vagina 27,260 740,944,444 34,886 891,986,887 3.6791 3.9110 0.9407 (0.9259, 0.9557) −0.063 (− 0.08, − 0.0463) −0.0277 (− 0.0348, − 0.0205) 57.22 3.91E-14 1.32
22 AML 42,798 755,946,352 56,422 898,917,035 5.6615 6.2767 0.902 (0.8907, 0.9134) −0.1086 (− 0.1227, − 0.0948) −0.0469 (− 0.0526, − 0.0412) 259.15 0.0714 1.46
23 Oropharynx 115,052 755,874,098 151,716 898,821,741 15.2211 16.8794 0.9018 (0.8949, 0.9087) −0.1089 (− 0.1175, − 0.1005) −0.047 (− 0.0504, − 0.0435) 700.30 2.27E-06 1.46
24 Thyroid 109,996 755,879,154 150,180 898,823,277 14.5521 16.7085 0.8709 (0.8642, 0.8777) −0.1482 (− 0.1571, − 0.1393) −0.0626 (− 0.0661, − 0.0592) 1214.15 2.64E-08 1.56
25 Liver 86,113 755,903,037 118,781 898,854,676 11.3921 13.2147 0.8621 (0.8545, 0.8697) −0.16 (− 0.1702, − 0.1498) −0.0672 (− 0.0712, − 0.0633) 1101.47 3.10E-42 1.59
26 Myeloma 57,433 755,931,717 80,524 898,892,933 7.5976 8.9581 0.8481 (0.8391, 0.8573) − 0.1791 (− 0.1917, − 0.1665) −0.0745 (− 0.0793, − 0.0698) 911.59 0.0035 1.64
27 Kidney 149,860 755,839,290 212,711 898,760,746 19.8270 23.6671 0.8377 (0.8322, 0.8433) −0.1936 (− 0.2016, − 0.1858) −0.08 (− 0.083, − 0.0771) 2762.42 1.98E-14 1.67
28 CML 17,167 738,183,602 25,089 892,477,941 2.3256 2.8112 0.8273 (0.8114, 0.8435) −0.2088 (− 0.2325, − 0.1856) −0.0848 (− 0.0934, − 0.0763) 367.62 1.32E-58 1.71