Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer incidence 2003–2017: part 2 – categorical bivariate analysis and attributable fractions

Reece, Albert Stuart; Hulse, Gary Kenneth

doi:10.1186/s13690-022-00812-7

Archives of Public Health

Table 5 AFE and PAR calculations by cancer type

From: Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer incidence 2003–2017: part 2 – categorical bivariate analysis and attributable fractions

Cancer	Total Cancers 2017, Surveillance Epidemiology and End Results Data	Cigarettes Attributable Fraction in the Exposed	Cigarettes Population Attributable Risk	THC Attributable Fraction in the Exposed	THC Population Attributable Risk	Cannabidiol Attributable Fraction in the Exposed	Cannabidiol Population Attributable Risk	Cigarette Cancer Numbers - Attributable Fraction in the Exposed	Cigarette Cancer Numbers - Population Attributable Risk	THC Cancer Numbers - Attributable Fraction in the Exposed	THC Cancer Numbers - Population Attributable Risk	Cannabidiol Cancer Numbers - Attributable Fraction in the Exposed	Cannabidiol Cancer Numbers - Population Attributable Risk
Lung	214,209	0.2696	0.1094	−0.2915	−0.1230	− 0.0271	−0.0074	57,749	23,441
Vulva.&.Vagina	6678	0.2065	0.0792	−0.0099	−0.0048	0.0397	0.0111	1379	529			265	74
Kidney	66,500	0.1375	0.0504	0.0031	0.0015	−0.1387	−0.0353	9141	3350	206	100
Colorectal	139,108	0.1142	0.0411	−0.3600	−0.1474	− 0.1120	−0.0290	15,880	5722
Cervix	12,695	0.1140	0.0411	−0.2330	−0.1010	− 0.3577	−0.0795	1447	521
Oropharynx	45,653	0.1020	0.0364	0.0169	0.0083	0.0063	0.0018	4656	1663	771	378	288	82
Penis	1342	0.0902	0.0305	−0.0400	−0.0191	−0.1827	−0.0310	121	41
Esophagus	16,891	0.0688	0.0233	−0.0957	−0.0445	0.1094	0.0334	1162	394			1848	564
All_Cancer	1,670,227	0.0396	0.0135	−0.0777	−0.0363	0.0179	0.0051
Brain	22,127	0.0390	0.0133	−0.0609	−0.0287	0.0765	0.0226	863	295			1693	500
CML	6680	0.0248	0.0083	0.0672	0.0337	−0.1208	−0.0298	165	56	449	225
Bladder	74,235	0.0159	0.0054	−0.0193	−0.0093	0.1901	0.0616	1182	398			14,112	4573
Hodgkins	8519	0.0137	0.0046	−0.0669	−0.0314	0.0604	0.0177	117	39			515	151
AML	14,928	0.0000	0.0000	0.1306	0.0679	0.0423	0.0122			1949	1014	631	182
Prostate	205,094	−0.0128	−0.0042	−0.4121	−0.1650	− 0.0260	−0.0071
Myeloma	25,732	−0.0204	−0.0067	0.0596	0.0299	−0.1676	−0.0418			1534	768
Breast	250,934	−0.0223	−0.0073	0.0416	0.0206	0.0746	0.0220			10,427	5171	18,720	5521
Pancreas	48,743	−0.0261	−0.0085	0.0977	0.0499	0.0109	0.0031			4760	2432	531	151
NH_Lymphoma	69,718	−0.0420	−0.0136	−0.0175	− 0.0084	0.0420	0.0121					2928	844
Ovary	19,918	−0.0610	−0.0195	− 0.1724	−0.0768	0.0059	0.0017					118	34
CLL	16,896	−0.0674	−0.0215	−0.0688	− 0.0322	0.0081	0.0023					137	39
Testis	10,000	−0.0705	−0.0224	0.0009	0.0009	−0.0297	−0.0261			9	9
ALL	5050	−0.1221	− 0.0365	0.1137	0.0656	−0.0626	− 0.0217			574	331
Thyroid	45,168	−0.1520	−0.0459	0.3278	0.1914	0.1489	0.0466			14,807	8645	6726	2105
Stomach	23,810	−0.2059	−0.0603	0.0160	0.0078	−0.1115	−0.0289			382	187
Kaposi	849	−0.2913	− 0.0621	−0.3838	− 0.2286	−0.8884	− 0.3189
Liver	32,357	−0.3057	−0.0845	0.3047	0.1754	−0.1028	−0.0268			9860	5675
Melanoma	85,362	−2.2928	−0.3018	0.5383	0.3613	−0.7015	−0.1303			45,949	30,845
Totals								93,860	36,450	91,677	55,780	48,510	14,819

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