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Table 3 The association between insulinemic indices and breast cancer in adult women in Imam Hossain and Shohada hospitals, Tehran between September 2015 and February 2016

From: The relationship between the insulinemic potential of diet and lifestyle and risk of breast cancer: a case-control study among iranian adult women

Variable

Tertiles of the insulinemic indices

1

2

3

P-trend

EDIH

 EDIH value cut points

<0.128

0.128 to 0.259

>0.259

 

 Median score

0.064

0.198

0.373

 

 cancer /control

28/88

56/89

49/88

 

 Crude

Ref (1.00)

1.95 (1.14 – 3.36)

1.73 (1.00 – 3.00)

0.094

 Model 1a

Ref (1.00)

2.00 (1.16 – 3.47)

2.85 (1.05 – 3.23)

0.059

 Model 2b

Ref (1.00)

1.80 (1.03 – 3.17)

1.81 (1.02 – 3.23)

0.068

 Model 3c

Ref (1.00)

2.00 (1.12 – 3.6)

2.24 (1.21 – 4.12)

0.016

EDIR

 EDIR value cut points

<0.733

0.733 to 1.044

>1.044

 

 Median score

0.578

0.867

1.288

 

 cancer /control

51/88

44/89

38/88

 

 Crude

Ref (1.00)

0.84 (0.51 – 1.39)

0.74 (0.44 – 1.25)

0.265

 Model 1a

Ref (1.00)

0.86 (0.52 – 1.43)

0.74 (0.44 – 1.25)

0.259

 Model 2b

Ref (1.00)

0.87 (0.52 – 1.46)

0.76 (0.44 – 1.30)

0.318

 Model 3c

Ref (1.00)

0.90 (0.57 – 1.54)

0.94 (0.51 – 1.74)

0.846

ELIH

 ELIH value cut points

<1.302

1.302 to 1.586

>1.586

 

 Median score

1.170

1.452

1.786

 

 cancer /control

33/87

53/87

47/86

 

 Crude

Ref (1.00)

1.58 (0.93 – 2.68)

1.46 (0.85 – 2.49)

0.206

 Model 1a

Ref (1.00)

1.50 (0.88 – 2.55)

1.40 (0.80 – 2.39)

0.287

 Model 2b

Ref (1.00)

1.56 (0.90 – 2.71)

1.49 (0.85 – 2.61)

0.202

 Model 3d

Ref (1.00)

1.50 (0.86 – 2.62)

1.43 (0.81 – 2.53)

0.255

ELIR

 ELIR value cut points

<4.543

4.543 to 6.486

>6.486

 

 Median score

3.882

5.420

7.761

 

 cancer /control

39/87

57/88

37/87

 

 Crude

Ref (1.00)

1.42 (0.86 – 2.35)

0.96 (0.56 – 1.45)

0.732

 Model 1a

Ref (1.00)

1.41 (0.85 – 2.34)

0.97 (0.56 – 1.67)

0.754

 Model 2b

Ref (1.00)

1.48 (0.88 – 2.51)

1.03 (0.58 – 1.81)

0.913

 Model 3d

Ref (1.00)

1.65 (0.96 – 2.83)

1.29 (0.69 – 2.38)

0.527

  1. aModel 1: adjusted for age and age at first pregnancy
  2. bModel 2: adjusted for model 1 and family history of cancer (yes, no), menopausal status (yes, no), anti-inflammatory drugs (yes, no), and vitamin D supplement (yes, no)
  3. cModel 3: adjusted for model 2 and energy, BMI, physical activity, and smoking
  4. dModel 3 adjusted for model 2 and energy and smoking