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Table 1 Summary of results from reviewed articles

From: Overview of the role of robots in upper limb disabilities rehabilitation: a scoping review

Ref

Country

Year

Study type

Study aim

Illness or accident leading to disability

Level of disability

Use of telerehabilitation

Use games and virtual reality

Hwang [66]

Republic of Korea

2012

Randomized controlled trials (RCT)

Evaluating robot-assisted hand and finger rehabilitation in stroke patients

Stroke

Fingers

 

Carpinella [26]

Italy

2012

Pilot study

Comparing two reaching tasks (RT) and objects’ reaching and manipulation (RMT) protocols for upper extremity robot-based rehabilitation in MS patients

Multiple sclerosis (MS)

Upper limb

  

Hu [56]

USA

2013

Experimental study

Investigating the effectiveness of robot-assisted upper limb training in stroke patients

Stroke

Fingers and wrist

 

Squeri [57]

Italy

2014

Pilot study

Developing a novel therapeutic protocol aimed at restoring wrist functionality in chronic stroke patients

Stroke

Wrist and forearm

 

Sale [76]

Italy

2014

RCT

Evaluating the effects of robot-assisted hand therapy compared to intensive occupational therapy in stroke patients

Stroke

Hand

  

Sale [27]

Italy

2014

Before and after

Determining the short-term and long-term changes in the motor performance of patients with chronic hemiparesis after using a rehabilitation robot

Chronic hemiparesis

Upper limb

  

Klamroth-Marganska [70]

Switzerland

2014

RCT

Evaluation of the effect of a skeleton robot in training the injured arm compared to conventional treatment

Stroke

Arm, elbow and shoulder

 

Hsieh [58]

Taiwan

2014

Observational cohort study

Investigating the predictors of minimal clinically important changes on outcome measures after robot-assisted therapy

Stroke

Wrist and forearm

  

Pennati [28]

Italy

2015

RCT

Investigating the effect of combining a short robotic exercise and chemical neurolysis in reducing spasm and improving function in patients with stroke

Stroke

Upper limb

  

McCabe [29]

USA

2015

RCT

Investigating the effect of using robotics on motor learning of the upper limbs of chronic and injured stroke survivors

Stroke

Upper limb

  

Chen [59]

China

2015

Not mentioned

Design and development of a cable wrist robotic rehabilitation device for motor training or assisting people with motor disabilities in the upper limb.

Stroke

Wrist and arm

 

Vanmulken [71]

Netherlands

2015

Feasibility study

Investigating the feasibility of tactile robot technology in improving arm and hand performance and skill in people with cervical spinal cord injury

Spinal cord injury (C-SCI)

Arm and hand

  

Gilliaux [30]

Belgium

2015

RCT

Evaluating the effectiveness of robot-assisted therapy in children with cerebral palsy

Cerebral Palsy

Upper limb

 

Taveggia [31]

Italy

2016

RCT

Evaluating the effectiveness of robotic-assisted movement and activity in upper limb rehabilitation in hospitalized patients after stroke

Stroke

Upper limb

 

Biggar [77]

United Kingdom

2016

Feasibility Study

Design and development of a wearable robotic glove to assist in the rehabilitation of patients at home

Stroke

Hand

  

Orihuela-Espina [78]

Mexico

2016

RCT

Determining the effectiveness of robot-based treatments in the motor improvement of stroke patients

Stroke

Hand

  

Song [32]

China

2016

Not mentioned

Development and design of a robot for upper limb telerehabilitation after a stroke

Stroke

Upper limb

Vanoglio [79]

Italy

2017

RCT

Evaluating the feasibility and effectiveness of hand and arm rehabilitation with the help of a robot in subacute hemiplegic patients

Stroke

Hand

  

Trujillo [33]

Italy

2017

Not mentioned

Assessing the relationship between quantitative electroencephalography (QEEG) measures and motor outcome in chronic stroke patients undergoing a robot-assisted rehabilitation program to predict motor recovery

Stroke

Upper limb

  

Saita [34]

Japan

2017

Pilot study

Investigating the effects of robot-assisted rehabilitation and botulinum toxin in the treatment of paretic arm with spasticity in stroke patients

Stroke

Upper limb

  

Nam [80]

Hong Kong

2017

RCT

Investigating the effects of robotic-assisted rehabilitation and training on the upper limbs of people with chronic stroke

Stroke

Hand and elbow

  

McKenzie [60]

USA

2017

Cross sectional

Validation and evaluation of the effect of a rehabilitation robot in improving arm motor function after stroke

Stroke

Wrist and fingers

 

Kim [72]

USA

2017

RCT

Comparison of long-term effects of external and internal focus after robot-assisted arm training

Stroke

Arm and shoulder

 

Bishop [67]

Columbia

2017

Pilot Study

Investigating the effect of training with a robotic system on paralysis and hand function in hemiparesis patients

Hemiparesis

Fingers

 

Housley [61]

USA

2017

Pilot study

Investigating the improvement of upper limb function and quality of life due to the use of a robot skeleton

Stroke

Wrist

Hsieh [35]

Taiwan

2017

RCT

Investigating the therapeutic effects of robotic priming on daily function, movement disorders, and quality of life in stroke patients

Stroke

Upper limb

  

Gandolfi [36]

Italy

2018

RCT

Comparison of the effect of robot-assisted hand training on muscle activity, hand skills, and upper limb dysfunction

MS

Upper limb

 

Lee [74]

Korea

2018

Pilot study

Design, development and evaluation of a shoulder joint tracking module for upper limb rehabilitation robots

Stroke

Shoulders

  

Germanotta [37]

Italy

2018

Cross-sectional

Evaluation of validity, capability and reliability of a robotic device for upper limb rehabilitation

Stroke

Upper limb

  

Kim [38]

Korea

2018

Pilot stud

Evaluation of the effects of therapeutic exercise with a robot in improving the upper limb in patients with chronic stroke

Stroke

Upper limb

 

Villafañe [68]

Italy

2018

RCT

Evaluation of the effect of robot and occupational therapy in motor improvement of stroke patients

Stroke

Fingers, shoulder, and arm

 

Palermo [62]

Italy

2018

Before and after

Evaluation of the effects of robotic rehabilitation on ten subacute stroke survivors

Stroke

Shoulders, elbow, wrist

 

Iwamoto [39]

Japan

2018

Not mentioned

Determining the effects of using single-joint hybrid auxiliary limb in upper limb rehabilitation of stroke patients

Stroke

Upper limb

  

Kim [75]

South Korea

2019

RCT

Investigating the therapeutic effects of a shoulder robot on hemiplegic shoulder pain after stroke

Stroke

Shoulder

 

Dehem [40]

Belgium

2019

RCT

Evaluating the effectiveness of upper limb robotic-assisted treatment as an alternative to conventional treatment in the rehabilitation of stroke patients

Stroke

Upper limb

 

Hung [41]

Taiwan

2019

RCT

Investigating the effects of combined unilateral and bilateral hybrid therapy compared to robot-assisted therapy in patients with chronic stroke

Stroke

Upper Limb

  

Conroy [42]

USA

2019

RCT

Investigating the effectiveness of robot therapy on motor outcomes of patients with moderate to severe arm disability with chronic stroke

Stroke

Upper limb

 

Bonanno [43]

Italy

2019

Case series study

Investigating motor-functional improvement in multiple sclerosis patients after robot-assisted rehabilitation

MS

Upper limb

 

Leem [44]

Republic of Korea

2019

Retrospective study

Determining the effect of robot therapy on stroke patients according to the demographic and clinical characteristics of these patients

Stroke

Upper limb

 

Kim [45]

South Korea

2019

Before and after

Investigating the effect of sensory stimulation and upper limb function of stroke patients after rehabilitation with the help of robots and virtual reality

Stroke

Upper limb

 

Tartamella [46]

Italy

2020

Case study

Evaluation of the usefulness of a robotic intensive neural rehabilitation program to improve functional independence in a 57-year-old patient with BRN

Brainstem radionecrosis (BRN)

Upper limb

 

Solaro [47]

Italy

2020

RCT

Comparing robot-assisted training based on tactile or sensorimotor training in the rehabilitation of upper limb disabilities in multiple sclerosis patients

MS

Upper limb

 

Picelli [63]

Italy

2020

RCT

Evaluation of the effects of robot-assisted arm therapy in patients with distal radius injury

Distal radius fracture

Wrist and forearm

  

Kuo [69]

Taiwan

2020

Case series study

Investigating the effects of robot therapy in improving the upper limb disabilities of patients with cerebral palsy

Cerebral Palsy (CP)

Fingers

-

Aprile [48]

Italy

2020

RCT

Investigation of shoulder pain, motor function, and quality of life in stroke patients after upper limb rehabilitation after robotic or conventional treatment

Stroke

Upper limb

 

Aprile [49]

Italy

2020

Before and after

Evaluation of the effect of using three robots and a sensor-based system in the rehabilitation of upper limb disabilities

Stroke

Upper limb

 

Bouteraa [64]

Egypt

2020

Case study

Designing and developing a new robotic system for the rehabilitation of the upper extremities

Stroke

Arm, wrist, forearm

 

Kim [50]

US

2020

RCT

Investigating the effects of following instructions on upper limb movement status in chronic stroke survivors after using a rehabilitation robot

Stroke

Upper limb

 

Bui [51]

USA

2021

Cross-sectional

Investigating the effects of robotic rehabilitation in improving cognitive and movement disorders in adults with HIV and stroke

Stroke

Upper limb

 

Flynn [52]

Australia

2021

Not mentioned

Investigating the stability of treatment and rehabilitation of the upper limb with the help of a robot in stroke survivors

Stroke

Upper limb

  

Terranova [53]

Brazil

2021

RCT

Investigating the difference between robot-assisted therapy and restriction-induced movement therapy after using a rehabilitation program by chronic stroke patients.

Stroke

Upper limb

  

Shi [65]

China.

2021

Before and after

Investigating the clinical effectiveness of a soft robotic hand in fingers, wrist and elbow rehabilitation

Stroke

Fingers, wrist and elbow

  

Chen [73]

China

2021

RCT

Investigating the effects of robot-assisted arm training on arm motor performance, one-sided spatial neglect, social participation and daily life activities after stroke

Stroke

Arm

 

Qu [54]

China

2021

RCT

Investigating the effect of using robot-assisted training on upper limb function in stroke patients

Stroke

Upper limb

 

Abd [55]

Saudi Arabia

2022

RCT

Investigating the effects of rehabilitation exercises provided through games and robots on motor functions and upper limb spasticity in individuals with chronic stroke.

Stroke

Upper limb