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Table 4 Analysis of the risk factors associated with HBV infection in East Africa

From: Prevalence and predictors of hepatitis B virus (HBV) infection in east Africa: evidence from a systematic review and meta-analysis of epidemiological studies published from 2005 to 2020

   

Analysis of HBV prevalence

Analysis of heterogeneity of studies

Risk factor

Category

Number

Proportion%, (95%CI)

P value

I2, 95%CI

P het

Model

Age

< 20 years

9

4.796 (1.88 to 8.97)

 

80.6 (64.07 to 89.54)

< 0.0001

Random

 

> 20 years

9

5.74 (3.52 to 8.46)

0.28

89.27 (81.9 to 93.65)

< 0.0001

Random

Gravidity

Primigravida

5

2.84 (1.37 to 4.82)

 

81.6 (57.40 to 92.06)

0.0002

Random

 

Multigravida

5

3.84 (3.40 to 4.33)

0.0006*

32.98 (0.00 to 74.58

0.2015

Fixed

Marital status

Married

17

5.508 (3.35 to 8.17)

 

98.91 (98.69 to 99.1)

< 0.0001

Random

 

Not Married

17

8.644 (5.21 to 12.85)

< 0.0001*

96.98 (96.13 to 97.6)

< 0.0001

Random

History of STIs

Yes

5

7.33 (4.77 to 10.67)

 

25.7 (0.00 to 70.27)

0.2015

Fixed

 

No

5

4.41 (2.79 to 6.39)

0.5858

68.61 (19.22 to 87.8)

0.0126

Random

Education Level

Primary & below

11

6.096 (4.42 to 8.02)

 

83.49 (71.9 to 90.29)

< 0.0001

Random

 

Secondary & above

11

5.917 (4.374 to 7.676)

0.6434

73.11 (50.84 to 85.3)

0.0001

Random

History of blood transfusion

Yes

10

11.057 (5.84 to 17.68)

 

79.6 (63.2 to 88.72)

< 0.0001

Random

 

No

10

4.915 (3.492 to 6.567)

< 0.0001*

89.5 (82.74 to 93.56)

< 0.0001

Random

History of scarification

Yes

4

8.102 (4.47 to 12.696)

 

89.7 (78.79 to 95.0)

< 0.0001

Random

 

No

4

5.049 (3.318 to 7.120)

< 0.0001*

84.4 (65.09 to 93.04)

< 0.0001

Fixed

Alcohol use

Yes

4

7.37 (3.46to 12.6)

 

64.88 (0.00 to 88.09)

0.036

Random

 

No

4

3.48 (2.55 to 4.63)

0.4703

30.01 (0.00 to 74.53)

0.2322

Fixed

HIV sero-status

Positive

6

12.131 (7.92 to 17.52)

 

12.15 (0.00 to 78.35)

0.3374

Fixed

 

Negative

6

5.863 (3.082 to 9.461)

0.0030*

89.81 (80.5 to 94.67)

< 0.0001

Random

History of body piecing

Yes

3

3.813 (2.41 to 5.70)

 

59.57 (0.00 to 88.48)

0.0843

Fixed

 

No

3

4.24 (2.903 to 5.95)

0.9394

0.00 (0.00 to 92.27)

0.6478

Fixed

History of surgery

Yes

7

13.2 (0.003 to 45.2)

 

99.50 (99.37 to 99.60)

< 0.0001

Random

 

No

7

4.85 (1.43 to 10.14)

< 0.0001*

97.32 (96.0 to 38.20

< 0.0001

Random

No of sexual partners

One

6

5.116 (3.124 to 7.566)

 

89.04 (78.8 to 94.34)

< 0.0001

Random

 

More than one

6

9.53 (5.509 to 14.512)

< 0.0001*

87.36 (74.9 to 93.65)

< 0.0001

Random

Employment

Formal

9

7.70 (2.38 to 15.69)

 

95.65 (93.51 to 97.1)

< 0.0001

Random

 

Non formal

9

10.48 (2.72 to 22.5)

0.333

98.6 (98.12 to 98.93)

< 0.0001

Random

Gender

Male

13

8.561 (6.66 to 10.675)

 

93.53 (90.6 to 95.54)

< 0.0001

Random

 

Female

13

6.986 (4.841 to 9.491)

0.0007*

96.63 (95.44 to 97.5)

< 0.0001

Random

  1. STIs Sexually Transmitted Infections
  2. *P value of risk factor < 0.05 statistically significant