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Table 2 Meta analysis results of the seroprevalence of CV-A16 (with 95 % confidence interval) in people by ethnicity, gender and age group

From: Seroprevalence of coxsackievirus A16 antibody among people of various age groups: a systematic review and meta-analysis

Group

Seroprevalence (%)

95 %CI (%)

Heterogeneity (P-value)

I2 (%)

Model

Begg’s (P-value)

Egger’s (P-value)

Ethnicity

 Overall

56.3

47.7 ~ 64.9

< 0.001

99.1

Random

0.228

0.105

 Chinese

55.1

44.1 ~ 66.1

< 0.001

98.8

Random

0.335

0.156

 Others

61.0

58.8 ~ 63.2

0.357

2.9

Fixed

0.224

0.135

Gender

 Male

56.1

45.2 ~ 67.1

< 0.001

98.0

Random

0.436

0.213

 Female

60.0

50.0 ~ 69.9

< 0.001

97.4

Random

0.640

0.202

Age

 < 1 yrs

17.5

12.4 ~ 24.5

< 0.001

88.6

Random

0.336

0.215

 1–3 yrs

37.5

31.2 ~ 45.5

< 0.001

92.3

Random

0.569

0.425

 4−5yrs

50.8

41.6 ~ 60.0

< 0.001

87.6

Random

0.758

0.628

 0 ~ 5 yrs

49.1

36.2 ~ 62.0

< 0.001

98.4

Random

0.837

0.266

 > 5 yrs

63.9

53.1 ~ 74.7

< 0.001

98.8

Random

0.115

0.380