Table 2 HDV genotypes and their geographical distribution
Genotype | Geographical location | Clinical features |
|---|---|---|
1 | Europe, North America and South Asia,Central and Northern Asia, eastern Mediterranian, and Middle East | Variable course |
2 | Yakutia region (Russia), Taiwan (China), and Japan | Higher rate of remission than genotype 1 |
3 | Amazon Basin | More severe, earlier onset of HCC, and outbreaks of lethal acute liver failure |
4 | Miyako Island (Japan), Taiwan (China) | Variant on the Miyako Islands associated with greater progression to cirrhosis than in Taiwan |
5 | Africa, Europe (migrants from Africa) | More associated with HCC than genotype 1 and other African genotypes Better prognosis with fewer episodes of hepatic decompensation |
6,7,8 | Africa, Europe (migrants from Africa) | Few data |