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Table 6 Compilation of the odds of experiencing wheezing, having ever been diagnosed with asthma, having ongoing asthma, or having eczema among the children whose mothers experienced asthma during pregnancy, compared to the offspring of non-asthmatic mothers, for all children, male only and female only regression models of different ages

From: Are wheezing, asthma and eczema in children associated with mother’s health during pregnancy? Evidence from an Australian birth cohort

Respiratory or allergic morbidities Age 0–1 Age 2–3 Age 4–5 Age 6–7 Age 8–9 Age 10–11 Age 12–13 Age 14–15
OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
N = 4977 N = 4485 N = 4264 N = 4088 N = 3922 N = 3574 N = 3097 N = 2960
Wheezing
All children
Wheezing = Yes 1.49 (1.13–1.97)* 1.83 (1.4–2.4)** 1.47 (1.08–1.99)Ϯ 1.8 (1.3–2.49)** 1.91 (1.34–2.71)** 2.47 (1.69–3.61)** 1.69 (1.02–2.78)Ϯ 1.27 (0.72–2.24)
  Wheezing = No (ref.)         
Male only
  Wheezing = Yes 1.5(1.03–2.18)Ϯ 1.93(1.34–2.76)** 1.77(1.20–2.63)* 2.07(1.35–3.18)** 1.97(1.22–3.17)* 3.28(2.01–5.34)** 1.56(0.78–3.11) 1.13(0.49–2.61)
  Wheezing = No (ref.)         
Female only
  Wheezing = Yes 1.46(0.94–2.24) 1.73(1.14–2.65)* 1.15(0.70–1.91) 1.59(0.96–2.66) 1.8(1.03–3.15)Ϯ 1.72(0.92–3.21) 1.67 (0.81–3.46) 1.47 (0.69–3.15)
  Wheezing = No (ref.)         
Ever diagnosed asthma
All children
  Ever had asthma = Yes   2.22 (1.65–3)** 2.34 (1.77–3.10)** 2.58 (1.94–3.44)** 2.42 (1.83–3.20)** 2.64 (1.96–3.56)** 2.9 (2.09–4.02)** 2.5 (1.78–3.52)**
  Ever had asthma = No (ref.)        
Male only
  Ever had asthma = Yes   2.76(1.86–4.11)** 2.75(1.86–4.07)** 2.69(1.81–3.98)** 2.87(1.93–4.28)** 3.04(1.98–4.67)** 2.66(1.69–4.18)** 2.35(1.46–3.79)**
  Ever had asthma = No (ref.)        
Female only
  Ever had asthma = Yes   1.77(1.10–2.86)Ϯ 2.01(1.30–3.10)* 2.44(1.57–3.81)** 1.98(1.30–3.01)** 2.29(1.46–3.59)** 3.42(2.06–5.69)** 2.83(1.73–4.62)**
  Ever had asthma = No (ref.)        
Ongoing asthma
All children
  Ongoing asthma = Yes   2.53 (1.85–3.46)** 3.29 (2.47–4.40)** 3.32 (2.45–4.50)** 2.75 (2.03–3.73)** 3.74 (2.72–5.15)** 3.18 (2.22–4.56)** 2.63 (1.79–3.87)**
  Ongoing asthma = No (ref.)        
Male only
  Ongoing asthma = Yes   3.17(2.10–4.77)** 4.09(2,76–6.08)** 3.30(2.17–5.00)** 2.74(1.79–4.20)** 3.66(2.36–5.68)** 3.17(1.93–5.21) 2.00(1.14–3.48)*
  Ongoing asthma = No (ref.)        
Female only
  Ongoing asthma = Yes   2.08(1.27–3.41)* 2.68(1.69–4.24)** 3.40(2.14–5.39)** 2.83(1.81–4.43)** 4.09(2.55–6.56)** 3.38(1.94–5.86)** 3.30(1.88–5.82)**
  Ongoing asthma = No (ref.)        
Eczema
All children
  Eczema = Yes 1.43 (1.06–1.94)Ϯ 1.2 (0.88–1.63) 1.45 (1.04–2.04)Ϯ 1.97 (1.4–2.77)** 1.38 (0.95–1.99) 1.56 (1.04–2.35)Ϯ 1.71 (1.09–2.67)Ϯ 1.09 (2.67–0.018)
  Eczema = No (ref.)         
Male only
  Eczema = Yes 1.46(0.96–2.21)Ϯ 1.13(0.73–1.75) 1.33(0.83–2.12) 2.08(1.29–3.36)* 1.76(1.05–2.96)Ϯ 2.18(1.24–3.84)* 1.16(0.58–2.34) 0.93(0.41–2.09)
  Eczema = No (ref.)         
Female only
  Eczema = Yes 1.39(0.90–2.15) 1.28(0.82–2.01) 1.62(0.99–2.66) 1.88(1.15–3.07) 1.11(0.67–1.85) 1.03(0.58–1.83) 2.15(1.21–3.83) 1.95(1.08–3.51)
Eczema = No (ref.)         
  1. Notes: Ϯ p < 0.05 & > 0.01, * p < 0.01 & > 0.001, ** p < 0.001, the regression models were adjusted for covariates outlined in ‘Control variables’ sub-section of ‘Methods’ section. Abbreviation: OR Odds Ratio; ref., reference category