| |
First 3 months
|
Last 3 months
|
|---|
| |
Adjusted HR (95%CI)
|
P-value
|
Adjusted HR (95%CI)
|
P-value
|
|---|
|
Sex
|
|
Male
|
a
| |
Reference
| |
|
Female
|
a
| |
0.83 (0.70–0.97)
|
0.02
|
|
Age in years
|
|
18 to 30 years
|
a
| |
Reference
| |
|
31 to 40 years
|
a
| |
0.97 (0.80–1.19)
|
0.80
|
|
41 to 50 years
|
a
| |
0.95 (0.75–1.20)
|
0.66
|
|
51 + years
|
a
| |
1.26 (1.02–1.55)
|
0.03
|
|
Patient type
|
|
New cases
|
a
| |
Reference
| |
|
Re-treatment cases
|
a
| |
1.57 (1.28–1.93)
|
<0.001
|
|
Nutrition status
|
|
Undernourished
|
0.96 (0.86–1.07)
|
0.47
|
a
| |
|
Normal BMI
|
Reference
| |
a
| |
|
Overweight
|
0.85 (0.73–0.98)
|
0.04
|
a
| |
|
HIV status
|
|
HIV uninfected
|
Reference
| |
Reference
| |
|
HIV infected on ARVS
|
1.08 (0.98–1.20)
|
0.13
|
1.65 (1.39–1.96)
|
<0.001
|
|
HIV infected not on ARVS
|
1.72 (1.28–2.30)
|
<0.001
|
2.56 (1.39–4.72)
|
0.003
|
|
Unknown HIV status
|
1.12 (0.74–1.68)
|
0.60
|
0.92 (0.34–2.46)
|
0.86
|
|
Underlying conditions
|
a
| |
2.24 (1.41–3.54)
|
0.001
|
|
TB diagnosis
|
|
Bacteriologically confirmed
|
a
| |
Reference
| |
|
Clinical signs
|
a
| |
0.82 (0.70–0.97)
|
0.02
|
|
Year of starting treatment
|
|
2012
|
Reference
| |
Reference
| |
|
2013
|
1.56 (1.20–2.02)
|
0.001
|
1.37 (0.95–1.98)
|
0.10
|
|
2014
|
1.55 (1.22–1.96)
|
<0.001
|
1.67 (1.16–2.40)
|
0.005
|
|
2015
|
1.58 (1.24–2.00)
|
<0.001
|
2.24 (1.57–3.20)
|
<0.001
|
|
2016
|
1.40 (1.11–1.76)
|
0.004
|
3.06 (2.17–4.31)
|
<0.001
|
|
2017
|
1.79 (1.42–2.25)
|
<0.001
|
2.80 (1.99–3.94)
|
<0.001
|
|
2018
|
1.93 (1.55–2.39)
|
<0.001
|
2.48 (1.77–3.47)
|
<0.001
|
|
2019
|
1.59 (1.27–1.99)
|
<0.001
|
2.30 (1.62–3.27)
|
<0.001
|
|
AUCs (95% CI)
|
0.60 (0.58–0.62)
|
0.64 (0.63–0.65)
|
- avariables were not selected for inclusion in multivariable model
