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Table 1 Significant Linear Regression Models by Substance

From: Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer incidence 2003–2017: part 1 – continuous bivariate analysis

Parameters

Model

E-Values

Cancer

Substance

Estimate

Std.Error

t-Statistic

P-Value

R.Squared

Adj.R.Squared

Sigma

t-Statistic

P-Value

E-Value—Point

E-Value—Lower

All_Cancer

Cigarettes

311.2758

26.2010

11.8803

6.10E-30

0.1587

0.1576

30.2276

141.1415

6.10E-30

2.35E + 04

5.02E + 03

All_Cancer

AUD

174.3105

77.5060

2.2490

0.0248

0.0067

0.0054

32.8455

5.0580

0.0248

249.76

3.16

Cervix

Analgesics

14.2232

2.9928

4.7525

2.41E-06

0.0293

0.0280

0.7557

22.5865

2.41E-06

5.49E + 07

4.76E + 04

Ovary

Analgesics

13.0281

3.4213

3.8079

1.52E-04

0.0190

0.0177

0.8639

14.5002

1.52E-04

1.82E + 06

1.58E + 03

Lung

Analgesics

156.2452

47.8675

3.2641

0.0011

0.0140

0.0127

12.0870

10.6545

0.0011

2.57E + 05

222.51

Prostate

AUD

294.0806

26.9078

10.9292

6.73E-26

0.1377

0.1365

11.4030

119.4472

6.73E-26

3.11E + 10

4.67E + 08

Ovary

AUD

16.4306

1.9686

8.3461

3.40E-16

0.0852

0.0840

0.8343

69.6578

3.40E-16

1.21E + 08

1.82E + 06

Colorectal

AUD

116.6256

14.8666

7.8448

1.50E-14

0.0760

0.0748

6.3002

61.5409

1.50E-14

4.14E + 07

6.21E + 05

Bladder

AUD

59.4761

7.6578

7.7668

2.65E-14

0.0746

0.0734

3.2452

60.3227

2.65E-14

3.50E + 07

5.25E + 05

CLL

AUD

13.3118

2.7643

4.8156

1.78E-06

0.0301

0.0288

1.1714

23.1903

1.78E-06

6.19E + 04

928.09

Hodgkins

AUD

5.4767

1.1398

4.8051

1.87E-06

0.0299

0.0286

0.4830

23.0892

1.87E-06

6.06E + 04

907.37

Esophagus

AUD

8.1151

2.0465

3.9653

8.06E-05

0.0214

0.0201

0.8377

15.7240

8.06E-05

1.35E + 04

173.64

NH_Lymphoma

AUD

17.1252

4.6200

3.7067

2.25E-04

0.0180

0.0167

1.9579

13.7398

2.25E-04

5.73E + 03

85.34

Thyroid

Cannabis

38.1264

3.6137

10.5504

2.35E-24

0.1295

0.1284

2.9671

111.3120

2.35E-24

2.40E + 05

2.74E + 04

Liver

Cannabis

18.7374

1.9860

9.4349

4.82E-20

0.1064

0.1052

1.6306

89.0176

4.82E-20

6.96E + 04

7.96E + 03

Breast

Cannabis

38.4836

5.4934

7.0054

5.50E-12

0.0616

0.0603

4.5104

49.0761

5.50E-12

4.71E + 03

538.42

Bladder

Cannabis

25.5306

4.0013

6.3805

3.09E-10

0.0516

0.0503

3.2853

40.7110

3.09E-10

2.36E + 03

269.10

Pancreas

Cannabis

6.9457

1.5165

4.5800

5.44E-06

0.0273

0.0260

1.2451

20.9766

5.44E-06

319.83

36.14

AML

Cannabis

2.7773

0.6876

4.0389

5.92E-05

0.0213

0.0200

0.5646

16.3128

5.92E-05

175.35

19.61

Lung

Cigarettes

206.6791

7.3636

28.0678

5.75E-119

0.5130

0.5123

8.4952

787.7991

5.75E-119

8.24E + 09

1.76E + 09

Colorectal

Cigarettes

102.7662

4.2610

24.1177

1.60E-95

0.4375

0.4367

4.9159

581.6646

1.60E-95

3.65E + 08

7.81E + 07

Cervix

Cigarettes

8.1118

0.5950

13.6326

5.88E-38

0.1990

0.1979

0.6865

185.8480

5.88E-38

9.36E + 04

2.00E + 04

Prostate

Cigarettes

92.4997

10.0923

9.1653

4.68E-19

0.1010

0.0998

11.6433

84.0036

4.68E-19

2.76E + 03

589.25

Vulva.&.Vagina

Cigarettes

2.8291

0.3193

8.8614

6.79E-18

0.1031

0.1018

0.3601

78.5253

6.79E-18

2.54E + 03

524.66

Ovary

Cigarettes

5.6544

0.7272

7.7751

2.50E-14

0.0748

0.0735

0.8390

60.4529

2.50E-14

921.01

196.48

Kidney

Cigarettes

10.5734

1.7983

5.8796

6.19E-09

0.0442

0.0429

2.0747

34.5703

6.19E-09

206.12

43.66

Penis

Cigarettes

0.5348

0.1174

4.5549

6.90E-06

0.0476

0.0453

0.1023

20.7467

6.90E-06

231.92

29.65

Brain

Cigarettes

3.1188

0.7234

4.3113

1.84E-05

0.0242

0.0229

0.8346

18.5875

1.84E-05

59.47

12.30

Bladder

Cigarettes

11.8284

2.8920

4.0901

4.78E-05

0.0219

0.0206

3.3364

16.7287

4.78E-05

49.86

10.24

Oropharynx

Cigarettes

4.6826

1.1454

4.0882

4.82E-05

0.0219

0.0205

1.3214

16.7133

4.82E-05

49.79

10.22

Hodgkins

Cigarettes

1.0813

0.4232

2.5549

0.0108

0.0087

0.0073

0.4883

6.5277

0.0108

14.49

2.59

Esophagus

Cigarettes

1.6896

0.7647

2.2095

0.0275

0.0068

0.0054

0.8440

4.8819

0.0275

11.84

1.77

Stomach

Cocaine

45.7579

6.4211

7.1262

2.43E-12

0.0636

0.0623

1.2139

50.7829

2.43E-12

1.58E + 15

1.29E + 11

Ovary

Cocaine

27.1820

4.5057

6.0328

2.53E-09

0.0464

0.0451

0.8518

36.3948

2.53E-09

8.18E + 12

6.66E + 08

Breast

Cocaine

126.7521

24.1889

5.2401

2.09E-07

0.0354

0.0341

4.5728

27.4586

2.09E-07

1.80E + 11

1.47E + 07

Kaposi

Cocaine

14.8095

4.4075

3.3601

8.98E-04

0.0422

0.0385

0.4019

11.2900

8.98E-04

7.32E + 14

2.43E + 06

Bladder

Cocaine

84.8740

17.5732

4.8298

1.66E-06

0.0302

0.0289

3.3221

23.3265

1.66E-06

2.50E + 10

2.04E + 06

Prostate

Cocaine

225.7327

64.4301

3.5035

4.86E-04

0.0161

0.0148

12.1802

12.2747

4.86E-04

4.22E + 07

3.44E + 03

Melanoma

Cocaine

21,958.5719

7636.0557

2.8756

0.0041

0.0109

0.0096

1443.5593

8.2693

0.0041

2.05E + 06

166.80

Hodgkins

Cocaine

5.5031

2.5863

2.1278

0.0337

0.0060

0.0047

0.4889

4.5275

0.0337

5.61E + 04

4.00

Colorectal

Cocaine

65.7878

34.5865

1.9021

0.0575

0.0048

0.0035

6.5384

3.6181

0.0575

1.89E + 04

1.00

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