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Table 2 Significant Linear Regression Models by Cannabinoid

From: Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer incidence 2003–2017: part 1 – continuous bivariate analysis

Parameters

Model

E-Values

Cancer

Substance

Term

Estimate

Std.Error

t-Statistic

P-Value

Adj.R.Squared

Sigma

t-Statistic

P-Value

E-Value—Point

E-Value—Lower

Prostate

Cannabidiol

CannbdRt

575.7886

40.1598

14.3374

2.28E-41

0.2145

10.8759

205.5620

2.28E-41

1.67E + 21

2.34E + 18

Thyroid

Cannabichromene

CannbdRt

156.7231

14.5353

10.7822

2.70E-25

0.1334

2.9586

116.2561

2.70E-25

1.72E + 21

2.74E + 17

Bladder

Cannabidiol

CannbdRt

138.8861

11.3748

12.2100

2.15E-31

0.1651

3.0805

149.0832

2.15E-31

1.32E + 18

1.84E + 15

Ovary

Cannabidiol

CannbdRt

35.7024

2.9444

12.1254

5.09E-31

0.1632

0.7974

147.0245

5.09E-31

9.91E + 17

1.38E + 15

Liver

Cannabichromene

CannbdRt

76.1608

8.0037

9.5157

2.42E-20

0.1068

1.6291

90.5482

2.42E-20

5.99E + 18

9.53E + 14

All_Cancer

Cannabidiol

CannbdRt

1081.1070

115.0938

9.3933

6.87E-20

0.1043

31.1692

88.2334

6.87E-20

1.02E + 14

1.43E + 11

Colorectal

Cannabidiol

CannbdRt

213.8584

22.9037

9.3373

1.10E-19

0.1032

6.2027

87.1847

1.10E-19

8.46E + 13

1.18E + 11

Thyroid

Cannabigerol

CannbdRt

83.9005

7.2622

11.5530

1.59E-28

0.1503

2.9295

133.4725

1.59E-28

4.17E + 11

5.05E + 09

Liver

Cannabigerol

CannbdRt

45.1026

3.9451

11.4325

5.22E-28

0.1476

1.5914

130.7011

5.22E-28

3.17E + 11

3.85E + 09

Breast

Cannabichromene

CannbdRt

149.2417

22.2143

6.7183

3.64E-11

0.0556

4.5216

45.1350

3.64E-11

2.22E + 13

3.53E + 09

Hodgkins

Cannabidiol

CannbdRt

13.1216

1.7461

7.5146

1.63E-13

0.0690

0.4729

56.4697

1.63E-13

1.85E + 11

2.59E + 08

Bladder

Cannabichromene

CannbdRt

97.3604

16.1873

6.0146

2.82E-09

0.0449

3.2948

36.1757

2.82E-09

9.54E + 11

1.52E + 08

Liver

Cannabinol

CannbdRt

31.8217

2.3327

13.6415

5.33E-38

0.1981

1.5435

186.0893

5.33E-38

2.81E + 08

1.91E + 07

Thyroid

Cannabinol

CannbdRt

58.0845

4.3115

13.4721

3.40E-37

0.1942

2.8528

181.4988

3.40E-37

2.23E + 08

1.51E + 07

Brain

Cannabidiol

CannbdRt

19.4078

3.0380

6.3884

2.94E-10

0.0505

0.8227

40.8119

2.94E-10

4.21E + 09

5.88E + 06

Lung

Cannabidiol

CannbdRt

258.5289

43.9435

5.8832

6.07E-09

0.0429

11.9006

34.6121

6.07E-09

7.70E + 08

1.08E + 06

NH_Lymphoma

Cannabidiol

CannbdRt

41.7851

7.1339

5.8573

7.05E-09

0.0426

1.9320

34.3079

7.05E-09

7.06E + 08

9.87E + 05

Pancreas

Cannabichromene

CannbdRt

28.7938

6.1125

4.7106

2.94E-06

0.0275

1.2442

22.1900

2.94E-06

2.80E + 09

4.46E + 05

Esophagus

Cannabidiol

CannbdRt

16.7282

3.1067

5.3846

9.84E-08

0.0375

0.8303

28.9943

9.84E-08

1.84E + 08

2.35E + 05

AML

Cannabichromene

CannbdRt

12.1345

2.7686

4.3830

1.34E-05

0.0237

0.5635

19.2103

1.34E-05

6.47E + 08

1.03E + 05

Breast

Cannabigerol

CannbdRt

74.3296

11.2175

6.6262

6.59E-11

0.0542

4.5251

43.9067

6.59E-11

6.21E + 06

7.52E + 04

Pancreas

Cannabigerol

CannbdRt

19.4504

3.0478

6.3818

3.07E-10

0.0504

1.2294

40.7277

3.07E-10

3.58E + 06

4.34E + 04

Pancreas

Cannabinol

CannbdRt

14.6579

1.8311

8.0047

4.57E-15

0.0777

1.2116

64.0760

4.57E-15

1.21E + 05

8.20E + 03

AML

Cannabigerol

CannbdRt

7.5386

1.3877

5.4326

7.52E-08

0.0367

0.5598

29.5133

7.52E-08

4.20E + 05

5.09E + 03

AML

Cannabinol

CannbdRt

6.2884

0.8313

7.5646

1.14E-13

0.0698

0.5501

57.2228

1.14E-13

6.59E + 04

4.48E + 03

Breast

Cannabinol

CannbdRt

39.0905

6.8898

5.6737

2.00E-08

0.0400

4.5589

32.1904

2.00E-08

4.89E + 03

331.75

Breast

Cannabidiol

CannbdRt

58.3586

17.0595

3.4209

6.58E-04

0.0141

4.6200

11.7025

6.58E-04

1.96E + 05

274.11

Bladder

Cannabigerol

CannbdRt

31.9672

8.2808

3.8604

1.23E-04

0.0182

3.3404

14.9026

1.23E-04

1.21E + 04

146.30

Oropharynx

Cannabinol

CannbdRt

9.3388

1.9902

4.6924

3.21E-06

0.0273

1.3169

22.0189

3.21E-06

1.27E + 03

85.68

Stomach

Cannabidiol

CannbdRt

12.7562

4.6084

2.7680

0.0058

0.0088

1.2480

7.6621

0.0058

2.19E + 04

30.11

CML

Cannabinol

CannbdRt

2.3785

0.6433

3.6974

2.36E-04

0.0184

0.3850

13.6708

2.36E-04

552.10

27.73

Testis

Cannabinol

CannbdRt

8.0518

1.8461

4.3615

1.47E-05

0.0235

2.1897

19.0228

1.47E-05

56.28

12.14

Oropharynx

Cannabigerol

CannbdRt

8.5809

3.2973

2.6024

0.0094

0.0076

1.3301

6.7725

0.0094

708.47

8.06

Kidney

Cannabinol

CannbdRt

8.6788

3.1913

2.7195

0.0067

0.0085

2.1117

7.3957

0.0067

83.70

5.16

Thyroid

THC

CannbdRt

2.8220

0.2096

13.4665

3.62E-37

0.1941

2.8531

181.3454

3.62E-37

4.35

3.74

Liver

THC

CannbdRt

1.5118

0.1140

13.2611

3.36E-36

0.1893

1.5521

175.8566

3.36E-36

4.29

3.68

Pancreas

THC

CannbdRt

0.6960

0.0892

7.8048

2.01E-14

0.0741

1.2140

60.9153

2.01E-14

2.76

2.32

AML

THC

CannbdRt

0.3032

0.0404

7.5007

1.80E-13

0.0687

0.5504

56.2607

1.80E-13

2.69

2.25

Breast

THC

CannbdRt

1.9686

0.3343

5.8882

5.89E-09

0.0430

4.5517

34.6715

5.89E-09

2.33

1.93

Oropharynx

THC

CannbdRt

0.4108

0.0970

4.2358

2.56E-05

0.0221

1.3204

17.9420

2.56E-05

1.99

1.60

CML

THC

CannbdRt

0.0974

0.0317

3.0756

0.0022

0.0124

0.3862

9.4592

0.0022

1.83

1.39

Testis

THC

CannbdRt

0.3272

0.0880

3.7205

2.14E-04

0.0169

2.1972

13.8421

2.14E-04

1.55

1.33

Kidney

THC

CannbdRt

0.3065

0.1555

1.9716

0.0490

0.0038

2.1166

3.8873

0.0490

1.54

1.03

Kaposi

Cannabidiol

CannbdRt

4.2681

2.8705

1.4869

0.1383

0.0047

0.4089

2.2108

0.1383

2.67E + 04

1.00

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