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Table 1 Numbers, calculated rates, extreme values, significance and e-values for tobacco

From: Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer incidence 2003–2017: part 2 – categorical bivariate analysis and attributable fractions

Cancer Numbers Calculated Rates Significance E-Values
Highest Quintile Cancer Count Highest Quintile Not Cancer Count Lowest Quintile Cancer Count Lowest Quintile Not Cancer Count Highest Quintile State Cancer Rate Lowest Quitile State Cancer Rate Rate Ratio (C.I.) Atrributable Fraction in the Exposed (C.I.) Population Attributable Risk (C.I.) Chi Squared P-Value E-Value - Point Estimate E-Value - Lower Bound
Lung 656,647 677,158,296 961,061 1,357,237,072 96.9710 70.8101 1.3695 (1.3652, 1.3738) 0.2696 (0.2673, 0.2719) 0.1094 (0.1083, 0.1106) 38,848.04 < 2.2E-320 2.07996 2.07042
Vulva.&.Vagina 29,220 669,780,121 46,922 1,355,478,100 4.3626 3.4616 1.2603 (1.242, 1.2788) 0.2065 (0.1948, 0.218) 0.0792 (0.0741, 0.0844) 967.76 8.12E-213 1.83294 1.79018
Kidney 158,246 677,656,697 273,505 1,357,924,628 23.3520 20.1414 1.1594 (1.1522, 1.1666) 0.1375 (0.1321, 0.1428) 0.0504 (0.0482, 0.0525) 2196.42 < 2.2E-320 1.58920 1.57099
Colorectal 389,377 677,425,566 691,163 1,357,506,970 57.4790 50.9141 1.1289 (1.1245, 1.1334) 0.1142 (0.1107, 0.1176) 0.0411 (0.0398, 0.0425) 3665.82 < 2.2E-320 1.51027 1.49851
Cervix 32,835 677,782,108 58,296 1,358,139,837 4.8445 4.2923 1.1286 (1.1135, 1.144) 0.114 (0.1019, 0.1259) 0.0411 (0.0364, 0.0457) 307.90 2.99E-69 1.50963 1.46890
Oropharynx 115,204 677,699,739 207,304 1,357,990,829 16.9993 15.2655 1.1136 (1.1056, 1.1216) 0.102 (0.0955, 0.1084) 0.0364 (0.0339, 0.0389) 857.67 6.63E-189 1.46916 1.44720
Esophagus 41,573 649,871,778 80,904 1,358,117,229 6.3972 5.9571 1.0739 (1.0612, 1.0867) 0.0688 (0.0577, 0.0797) 0.0233 (0.0194, 0.0273) 139.56 1.34E-32 1.35552 1.31619
Penis 4438 553,731,268 8680 1,190,377,950 0.8015 0.7292 1.0992 (1.0601, 1.1397) 0.0902 (0.0567, 0.1225) 0.0305 (0.0186, 0.0423) 26.28 2.95E-07 1.42936 1.31263
All_Cancer 4,097,024 673,717,919 7,884,694 1,350,313,439 608.1215 583.9159 1.0415 (1.0402, 1.0427) 0.0396 (0.0384, 0.0407) 0.0135 (0.0131, 0.0139) 4422.11 < 2.2E-320 1.24833 1.24383
Brain 53,859 677,761,084 103,713 1,358,094,420 7.9466 7.6366 1.0406 (1.0298, 1.0515) 0.039 (0.0289, 0.049) 0.0133 (0.0098, 0.0168) 56.11 6.85E-14 1.24608 1.20501
Bladder 185,938 677,629,005 366,650 1,357,831,483 27.4395 27.0026 1.0162 (1.0105, 1.0219) 0.0159 (0.0104, 0.0214) 0.0054 (0.0035, 0.0072) 31.77 1.74E-08 1.14438 1.11363
CML 16,596 669,959,025 32,750 1,355,621,500 2.4772 2.4159 1.0254 (1.0064, 1.0447) 0.0248 (0.0064, 0.0428) 0.0083 (0.0021, 0.0145) 6.93 0.008498621 1.18675 1.08680
Hodgkins 18,865 677,796,078 37,284 1,358,160,849 2.7833 2.7452 1.0139 (0.9963, 1.0318) 0.0137 (−0.0037, 0.0308) 0.0046 (− 0.0013, 0.0104) 2.38 0.122840457 1.13251 1.00
AML 40,264 677,774,679 80,681 1,358,117,452 5.9406 5.9407 1 (0.9881, 1.012) 0 (− 0.012, 0.0119) 0 (− 0.004, 0.004) 0.00 0.997775002 1.00414 NA
Prostate 479,151 677,335,792 972,452 1,357,225,681 70.7405 71.6500 0.9873 (0.9839, 0.9907) −0.0128 (− 0.0164, − 0.0094) − 0.0042 (− 0.0054, − 0.0031) 52.35 4.64E-13 1.12692 NA
Myeloma 54,005 677,760,938 110,422 1,358,087,711 7.9681 8.1307 0.98 (0.97, 0.9901) −0.0204 (− 0.031, − 0.01) −0.0067 (− 0.0101, − 0.0033) 14.80 1.20E-04 1.16470 NA
Breast 576,439 677,238,504 1,180,798 1,357,017,335 85.1161 87.0142 0.9782 (0.9751, 0.9813) −0.0223 (− 0.0255, − 0.0191) −0.0073 (− 0.0083, − 0.0063) 188.27 4.37E-43 1.17320 NA
Pancreas 112,830 677,702,113 231,985 1,357,966,148 16.6489 17.0833 0.9746 (0.9677, 0.9815) −0.0261 (− 0.0334, − 0.0188) −0.0085 (− 0.0109, − 0.0062) 50.36 1.28E-12 1.18970 NA
NH_Lymphoma 165,126 677,649,817 344,785 1,357,853,348 24.3675 25.3919 0.9597 (0.954, 0.9653) −0.042 (− 0.0482, − 0.0359) −0.0136 (− 0.0155, − 0.0117) 189.31 2.64E-43 1.25130 NA
Ovary 52,311 677,762,632 111,212 1,358,086,921 7.7181 8.1889 0.9425 (0.9328, 0.9524) −0.061 (− 0.0721, − 0.05) −0.0195 (− 0.0229, − 0.0161) 124.74 2.56E-29 1.31537 NA
CLL 44,694 677,770,249 95,596 1,358,102,537 6.5942 7.0389 0.9368 (0.9264, 0.9474) −0.0674 (− 0.0795, − 0.0555) −0.0215 (− 0.0251, − 0.0178) 129.75 2.06E-30 1.33573 NA
Testis 18,973 677,795,970 40,700 1,358,157,433 2.7993 2.9967 0.9341 (0.9182, 0.9504) −0.0705 (− 0.0891, − 0.0522) −0.0224 (− 0.028, − 0.0168) 60.10 8.99E-15 1.34525 NA
ALL 11,779 601,068,358 27,611 1,255,633,450 1.9596 2.1990 0.8911 (0.8721, 0.9106) −0.1221 (− 0.1466, − 0.0982) −0.0365 (− 0.0432, − 0.0299) 109.78 4.94E-26 1.49237 NA
Thyroid 97,552 677,717,392 225,182 1,357,972,951 14.3941 16.5822 0.868 (0.8616, 0.8746) −0.152 (− 0.1607, − 0.1434) −0.0459 (− 0.0483, − 0.0436) 1365.04 3.47E-300 1.57041 NA
Stomach 56,389 677,758,554 136,254 1,358,061,879 8.3199 10.0330 0.8293 (0.8212, 0.8374) −0.2059 (− 0.2178, − 0.1941) −0.0603 (− 0.0633, − 0.0572) 1401.96 1.05E-306 1.70413 NA
Kaposi 2824 277,888,455 10,419 794,070,351 1.0161 1.3122 0.7744 (0.7429, 0.8073) −0.2913 (− 0.3461, − 0.2387) −0.0621 (− 0.0716, − 0.0527) 146.00 6.53E-34 1.90462 NA
Liver 68,272 677,746,671 178,617 1,358,019,516 10.0733 13.1528 0.7659 (0.7591, 0.7727) −0.3057 (− 0.3172, − 0.2942) −0.0845 (− 0.0872, − 0.0819) 3534.82 < 2.2E-320 1.93740 NA
Melanoma 83,366 677,731,577 550,065 1,357,648,068 12.3008 40.5160 0.3036 (0.3014, 0.3058) −2.2928 (− 2.3169, − 2.2689) −0.3018 (− 0.303, − 0.3005) 115,616.10 < 2.2E-320 6.04057 NA