Model 1 HR(95%CI) P | Model 2 HR(95%CI) P | Model 3 HR(95%CI) P | |
---|---|---|---|
All-cause mortality | |||
Continuous | 1.46 ( 1.40, 1.52) < 0.001 | 1.25 ( 1.19, 1.30) < 0.001 | 1.23 ( 1.16, 1.30) < 0.001 |
Lead quartiles | |||
Q1 | 1.0 | 1.0 | 1.0 |
Q2 | 1.51 ( 1.21, 1.89) < 0.001 | 1.14 ( 0.93, 1.39) 0.22 | 1.21 ( 0.99, 1.48) 0.06 |
Q3 | 1.94 ( 1.61, 2.33) < 0.001 | 1.21 ( 1.00, 1.46) 0.05 | 1.26 ( 1.05, 1.52) 0.01 |
Q4 | 3.06 ( 2.61, 3.60) < 0.001 | 1.75 ( 1.47, 2.08) < 0.001 | 1.73 ( 1.43, 2.10) < 0.001 |
p for trend | < 0.001 | < 0.001 | < 0.001 |
Cardiovascular disease mortality | |||
Continuous | 1.60 ( 1.48, 1.72) < 0.001 | 1.35 ( 1.24, 1.48) < 0.001 | 1.34 ( 1.21, 1.48) < 0.001 |
Lead quartiles | |||
Q1 | 1.0 | 1.0 | 1.0 |
Q2 | 1.59 ( 1.11, 2.26) 0.01 | 1.13 ( 0.80, 1.60) 0.47 | 1.22 ( 0.87, 1.72) 0.24 |
Q3 | 2.20 ( 1.64, 2.96) < 0.001 | 1.26 ( 0.93, 1.72) 0.14 | 1.32 ( 0.95, 1.83) 0.09 |
Q4 | 3.83 ( 2.91, 5.05) < 0.001 | 2.01 ( 1.51, 2.67) < 0.001 | 2.00 ( 1.47, 2.73) < 0.001 |
p for trend | < 0.001 | < 0.001 | 0.005 |