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Table 2 Questions regarding knowledge needed to decide about undergoing NIPT

From: Preconception education program for non-invasive prenatal testing focused on interest in genetics among female university students in Japan: a quasi-experimental study comparing pre-intervention, post-intervention, and three-month follow-up results

1. About knowledge of genetics

(1) One can see a gene with the naked eye. (false)

(2) Healthy parents can have a child with a hereditary disease. (true)

(3) The onset of certain diseases is due to genes, environment, and lifestyle. (true)

(4) A gene is a disease. (false)

(5) The carrier of a disease gene may be completely healthy. (true)

(6) All serious diseases are hereditary. (false)

(7) A gene is a molecule that controls hereditary characteristics. (true)

(8) Genes are inside cells. (true)

(9) The child of a disease gene carrier is always a carrier of the same disease gene. (false)

(10) A gene is a piece of DNA. (true)

(11) A gene is a cell. (false)

(12) A gene is a part of a chromosome. (true)

(13) Different body parts include different genes. (false)

(14) Genes are bigger than chromosomes. (false)

(15) It has been estimated that a person has about 25,000 genes. (true)

2. About knowledge of prenatal testing

(1) Ultrasound examination can detect all fetal abnormalities. (false)

(2) It is necessary for pregnant women to undergo prenatal testing. (false)

(3) There is a risk of miscarriage in prenatal testing. (true)

(4) If a fetal abnormality is detected, a pregnant woman is able to have an abortion at any time during pregnancy. (false) *

(5) There are fetal therapies for almost all fetal abnormalities. (false)

  1. Note.* In Japan, termination of a pregnancy is allowed at less than 22 weeks of pregnancy
  2. NIPT: non-invasive prenatal testing