Childhood obesity and risk of Alzheimer’s disease: a Mendelian randomization study

Table 1 Childhood obesity SNPs used to construct the instrument variables

chr	Position	SNP	Effect Allele	Other Allele	Beta	SE	p value	F
1	74,977,870	rs1040070	C	G	-0.1492	0.0269	2.77E-08	30.75887
1	177,913,519	rs10913469	C	T	0.1773	0.033	7.99E-08	28.86203
2	638,144	rs4854344	T	G	0.2445	0.0351	3.22E-12	48.51553
2	25,150,116	rs6752378	A	C	0.1695	0.0262	1.05E-10	41.84794
4	45,175,691	rs13130484	T	C	0.1434	0.0272	1.30E-07	27.79059
4	113,311,790	rs4833407	A	C	0.1226	0.0265	3.88E-06	21.40063
4	130,731,284	rs4864201	C	T	-0.1355	0.0281	1.41E-06	23.24894
5	66,149,113	rs28636	T	C	-0.1474	0.0316	3.07E-06	21.75495
12	50,247,468	rs7138803	A	G	0.1672	0.0271	6.50E-10	38.06021
13	54,064,981	rs9568856	A	G	0.1909	0.0395	1.36E-06	23.35366
16	53,825,488	rs9941349	T	C	0.1978	0.0267	1.16E-13	54.87409
17	46,669,430	rs9299	T	C	0.1343	0.0282	1.91E-06	22.67729
18	57,839,769	rs571312	A	C	0.1986	0.0309	1.25E-10	41.30273
18	38,765,659	rs17697518	T	C	0.1855	0.0389	1.85E-06	22.73662
19	34,315,896	rs256335	T	C	0.1214	0.0262	3.72E-06	21.46703

Chr, chromosome; SNP, single-nucleotide polymorphism; Beta, beta coefficient; SE, standard error

ISSN: 2049-3258