Table 3 HR (95% CI) in frailty associated with log-urinary heavy metals levels according to cox regression
Urine Metals (log-µg/g creatinine) | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |
Cadmium | Â | Â | Â | Â | Â | Â |
 Continuous | 1.77 (1.44, 2.19) | < 0.01 | 1.95 (1.57, 2.43) | < 0.01 | 1.96 (1.53, 2.52) | < 0.01 |
 Q1 | Reference |  | Reference |  | Reference |  |
 Q2 | 1.38 (1.06, 1.79) | 0.02 | 1.32 (1.02, 1.72) | 0.04 | 1.36 (1.04, 1.77) | 0.03 |
 Q3 | 1.43 (1.11, 1.84) | 0.01 | 1.44 (1.11, 1.86) | 0.01 | 1.48 (1.13, 1.94) | < 0.01 |
 Q4 | 1.97 (1.54, 2.52) | < 0.01 | 1.95 (1.52, 2.51) | < 0.01 | 1.93 (1.45, 2.56) | < 0.01 |
 P for trend | 2.19 (1.65, 2.90) | < 0.01 | 2.21 (1.66, 2.95) | < 0.01 | 2.12 (1.53, 2.94) | < 0.01 |
Cobalt | Â | Â | Â | Â | Â | Â |
 Continuous | 1.33 (1.16, 1.52) | < 0.01 | 1.24 (1.08, 1.42) | < 0.01 | 1.30 (1.13, 1.49) | < 0.01 |
 Q1 | Reference |  | Reference |  | Reference |  |
 Q2 | 1.09 (0.86, 1.38) | 0.48 | 1.13 (0.89, 1.43) | 0.32 | 1.29 (1.01, 1.65) | 0.04 |
 Q3 | 1.09 (0.86, 1.39) | 0.48 | 1.14 (0.90, 1.46) | 0.28 | 1.30 (1.02, 1.67) | 0.04 |
 Q4 | 1.40 (1.11, 1.76) | < 0.01 | 1.33 (1.06, 1.68) | 0.02 | 1.57 (1.23, 2.01) | < 0.01 |
 P for trend | 1.65 (1.18, 2.30) | < 0.01 | 1.50 (1.07, 2.09) | 0.02 | 1.81 (1.29, 2.56) | < 0.01 |
Tungsten | Â | Â | Â | Â | Â | Â |
 Continuous | 1.25 (0.72, 2.16) | 0.43 | 1.28 (0.75, 2.19) | 0.36 | 1.23 (0.71, 2.13) | 0.45 |
 Q1 | Reference |  | Reference |  | Reference |  |
 Q2 | 1.29 (1.01, 1.65) | 0.04 | 1.25 (0.98, 1.60) | 0.08 | 1.20 (0.94, 1.54) | 0.15 |
 Q3 | 1.22 (0.96, 1.57) | 0.11 | 1.22 (0.95, 1.56) | 0.12 | 1.25 (0.97, 1.61) | 0.08 |
 Q4 | 1.31 (1.03, 1.67) | 0.03 | 1.34 (1.05, 1.72) | 0.02 | 1.30 (1.01, 1.66) | 0.04 |
 P for trend | 2.18 (0.84, 5.62) | 0.11 | 2.60 (0.99, 6.80) | 0.05 | 2.29 (0.87, 6.05) | 0.09 |